Results 81 to 90 of about 232,533 (233)

A narrative synthesis on the epidemiology of Clostridioides difficile

One Health & Risk Management, 2021
Introduction. Clostridium difficile has been identified as the leading cause of antibiotic therapy-associated diarrhea and colitis, which has evolved from sporadic complications of antimicrobial therapy to severe, sometimes fatal events that have ...
Diana SPATARU, Angela PARASCHIV, Ion BERDEU   +2 more
doaj  

How do hospital professionals involved in a randomised controlled trial perceive the value of genotyping vs. PCR-ribotyping for control of hospital acquired C. difficile infections? [PDF]

, 2014
Background: Despite scientific advances in typing of C. difficile strains very little is known about how hospital staff use typing results during periods of increased incidence (PIIs). This qualitative study, undertaken alongside a randomised controlled
Peter M Hawkey, Hawkey, Peter M., Szczepura, Ala, Parsons, Helen, Katherine Hardy, Susan Manzoor, Gossain, Savita, Savita Gossain, Hardy, K. (Katherine), Stallard, Nigel, Nigel Stallard, Manzoor, Susan, Ala Szczepura, Hardy, Katherine, Helen Parsons, Hawkey, P. M. (Peter M.), Szczepura, Ala; id_orcid   +16 more
core   +2 more sources

Patient Safety and Organisational Accountability: Reassessing Criminal Liability Frameworks in Healthcare

The Modern Law Review, EarlyView.
Serious harm in healthcare often results from systemic failures, yet criminal accountability remains largely addressed through homicide law, gross negligence manslaughter and health‐and‐safety offences, frameworks that emphasise individual culpability and are ill‐suited to addressing organisational failings.
Sarah Bennett, Amel Alghrani
wiley   +1 more source

Antibiotic Associated Diarrhea in Hospitalized Adult Patients

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2018
Background: Antibiotic associated diarrhea (AAD) occurs from the first initiation until 2 months of the end of antibiotic treatment. The aims of this study were to know the incidence of AAD, Clostridium difficile infection and other gastrointestinal ...
Marcellus Simadibrata, Lie Khie Chen, Diana Aulia, Ina Sutanto Timan   +3 more
doaj   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Recurrent Pseudomembranous Colitis in an Ovarian Cancer Patient Undergoing Carboplatin Chemotherapy

Case Reports in Obstetrics and Gynecology, 2016
Background. Diarrhea is a common problem in ovarian cancer patients undergoing chemotherapy and Clostridium difficile infection has been identified as a cause.
Valerie A. Allen, Kelly J. Manahan, John P. Geisler   +2 more
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Equine coronavirus: Investigating seroconversion and faecal shedding patterns in naturally occurring field infections

Equine Veterinary Education, EarlyView.
Summary Background Equine coronavirus (ECoV) is an increasingly recognised cause of pyrexia and enteric disease in the horse. Objectives To (1) evaluate if horses seroconvert after clinical ECoV infection and (2) investigate the pattern of faecal excretion of ECoV to determine the optimal testing moment with the overall aim of helping veterinarians in ...
H. C. Smith, M. J. P. Theelen, R. M. A. C. Houben, R. van den Boom, L. van den Wollenberg, V. van Leeuwen, C. van Maanen   +6 more
wiley   +1 more source

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source

A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients

Guoji laonian yixue zazhi
[Objective] To investigate the risk factors of Clostridium difficile infection in elderly inpatients and provide the theoretical basis for the prevention and treatment of Clostridium difficile infection.
Yang Chen, Yingjun Gong, Cui Li, Huan Li, Jia Chen, Hui Su, Xiaoming Wang, Xiaoxuan Ning   +7 more
doaj   +1 more source