Results 101 to 110 of about 47,365 (201)
The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun +29 more
wiley +1 more source
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse +3 more
wiley +1 more source
Yuyao Hao,1,* Jianhui Li,2,* Shoujun Xie,1 Yanchao Liu,1 Hainan Wen1,3 1Department of Clinical Laboratory, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China; 2Department of Preventive ...
Hao Y, Li J, Xie S, Liu Y, Wen H
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ABSTRACT Area postrema syndrome (APS) is a rare neurological syndrome that presents a significant diagnostic challenge due to its nonspecific clinical manifestations, most commonly persistent nausea and vomiting, which frequently lead to initial misdiagnosis as a gastrointestinal disorder.
Andreea‐Gabriela Manole +4 more
wiley +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Perioperative Antibiotic Prophylaxis in Burn Patients: Protocol for a Systematic Review
ABSTRACT Background Burn injuries are associated with substantial morbidity and mortality worldwide, with infections representing a major complication. The desirable and undesirable effects of perioperative antibiotic prophylaxis in burn patients are unresolved.
Gustav Borghegn Blak Christensen +9 more
wiley +1 more source
Abstract The Qualified Presumption of Safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ) +26 more
wiley +1 more source

