Results 131 to 140 of about 55,730 (193)

Clinical Outcome Associated With Beta‐Lactam Allergy Labels in Hospitalized Patients in Belgium

open access: yesClinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background In the United States, beta‐lactam allergy labels (BLAL) are documented in 9%–16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling ...
Liesbeth Gilissen   +10 more
wiley   +1 more source

Clostridium difficile [PDF]

open access: yesAmerican Journal of Transplantation, 2004
openaire   +2 more sources

Preserving DNAzyme Stability and Activity in Stool Samples for Clinical Diagnostics

open access: yesChemistry–Methods, Volume 6, Issue 4, April 2026.
A RNA‐cleaving DNAzymes often lose activity in stool due to extensive nuclease‐mediated degradation. This work introduces a simple heparin‐based treatment that preserves DNAzyme integrity and catalytic function in this highly challenging matrix, enabling reliable pathogen‐responsive signaling in stool samples.
Soyeon Lee   +3 more
wiley   +1 more source

A Rare Case of Immune‐related Adverse Events Localized to the Small Intestine

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Enterocolitis is a common gastrointestinal manifestation of immune‐related adverse events (irAEs); however, only a few studies have reported on irAE enteritis with localized active inflammation in the small intestine. Here, we report the case of a 74‐year‐old man who developed diarrhea, abdominal pain, and oral intake difficulty and was ...
Ryo Morikawa   +9 more
wiley   +1 more source

Severe Bacteremia Caused by Clostridium butyricum Following Endoscopic Ultrasound‐Guided Peripancreatic Fluid Drainage for Walled‐off Necrosis: A Case Report

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a rare case of bacteremia caused by Clostridium butyricum following endoscopic ultrasound‐guided peripancreatic fluid drainage (EUS‐PFD) for walled‐off necrosis (WON) in a patient with alcoholic chronic pancreatitis. The patient underwent EUS‐PFD using a plastic stent (PS) for WON, initially with a good response.
Koichi Soga   +9 more
wiley   +1 more source

Restoration of Gut Microbiota and Metabolic Homeostasis by Lacticaseibacillus paracasei Zhang in Azithromycin‐Induced Dysbiosis

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu   +4 more
wiley   +1 more source

Effect and Mechanism of Acacetin Against Stress‐Induced Gastric Mucosal Damage: Network Pharmacology, Molecular Docking and Experimental Verification

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study evaluated Acacetin's therapeutic potential for stress‐induced gastric mucosal damage and investigated its potential mechanism. Based on network pharmacology and molecular docking, Acacetin demonstrated potential mucosal protective effects through multiple ferroptosis‐related targets.
Xin‐xin Zhang   +7 more
wiley   +1 more source

Deadly Diarrhea Caused by Co-Infection of Clostridium perfringens Type ST-865 and Clostridium difficile: A Case Report and Review of the Literature

open access: yesInfection and Drug Resistance
Yuyao Hao,1,* Jianhui Li,2,* Shoujun Xie,1 Yanchao Liu,1 Hainan Wen1,3 1Department of Clinical Laboratory, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China; 2Department of Preventive ...
Hao Y, Li J, Xie S, Liu Y, Wen H
doaj  

The Role of Gut Microbiome in Obesity and Weight Management: A Review of Current Evidence and Future Directions

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
The gut microbiome is critical in controlling host metabolism and body weight. Gut microbial composition and functionality are regulated by external factors such as diet, exercise, medications, and surgical procedures. The microbiome, in turn, affects energy balance, fat storage, and metabolic processes, leading to the development of obesity and weight
Ayesha Rehman   +6 more
wiley   +1 more source

Pancreas Transplantation in the Modern Era: Observations and Implications of Donor Pancreas Extraction Time

open access: yesClinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT There has been a worldwide reduction in pancreas transplant volume over the last decade. Understanding factors, such as procurement extraction time (ET), that play a key role in organ recovery can increase confidence in organ acceptance and improve organ utilization.
Michael A. Deal   +11 more
wiley   +1 more source

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