Results 81 to 90 of about 113,640 (277)

Clostridium difficile and the microbiota [PDF]

Journal of Clinical Investigation, 2014
Clostridium difficile infection (CDI) is the leading health care-associated illness. Both human and animal models have demonstrated the importance of the gut microbiota's capability of providing colonization resistance against C. difficile. Risk factors for disease development include antibiotic use, which disrupts the gut microbiota, leading to the ...
Vincent B. Young, Anna M. Seekatz
openaire   +2 more sources

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]

, 2020
Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan, Franc, Nathalie C, Guichard, Annabel, Roy, Sitara, Schwartz, Ruth   +4 more
core  

Synergistic efficacy of 405 nm light and chlorinated disinfectants for the enhanced decontamination of Clostridium difficile spores [PDF]

, 2016
The ability of Clostridium difficile to form highly resilient spores which can survive in the environment for prolonged periods causes major contamination problems.
Anderson, John G., Coia, John E., MacGregor, Scott J., Maclean, Michelle, Moorhead, Sian   +4 more
core   +1 more source

Liver Disease Predicts 30‐Day Postoperative Complications in Head and Neck Microvascular Surgery

The Laryngoscope, EarlyView.
While liver disease is known to affect surgical outcomes, its impact on head and neck microvascular free tissue transfer surgeries remains unexamined. This study uses the NSQIP national database to analyze the relationship between liver disease severity, determined by APRI and MELD‐Na scores, and postoperative complications.
Anish R. Kosanam, James R. Xu, Khashayar Arianpour, Danielle Bottalico, Eric D. Lamarre   +4 more
wiley   +1 more source

Examination of Clostridium difficile Contamination in beef meat distributed in Isfahan using culture and Multiplex-PCR method

Biological Journal of Microorganism, 2014
Introduction: With regard to increasing of community associated Clostridium difficile infection in recent years, the probable transmission of Clostridium difficile from food to human was supposed.
zahra Esfandiari, Mohammad Jalali, Hamid Ezzatpanah, Scott Weese, Mohammad Chamani   +4 more
doaj  

Assessment of the utility of repeat stool testing for Clostridium difficile stool toxin using enzyme immunoassay [PDF]

, 2015
The poor performance of toxin enzyme immunoassay (EIA) for laboratory testing for Clostridium difficile (C. difficile) infection (CDI) is well acknowledged. Guidelines published in recent years state that testing solely with EIA for detecting toxins A
Barbara, Christopher, Borg, Michael Angelo, Galea, Karl   +2 more
core   +1 more source

The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi, Anthony H.V. Schapira, Per Borghammer   +2 more
wiley   +1 more source

Perceptions of fecal microbiota transplantation for Clostridium difficile infection: factors that predict acceptance. [PDF]

, 2016
BackgroundDespite the effectiveness of fecal microbiota transplantation (FMT) for treating recurrent Clostridium difficile (C. difficile) infection, some patients are reluctant to accept this therapy.
Chen, Lea Ann, Hirsh, Jacqueline, Malter, Lisa, Mone, Anjali, Park, Leslie, Poles, Michael A, Price, Jennifer C, Tzimas, Demetrios   +7 more
core   +1 more source

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]

, 2018
Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch, Abt, Ananthakrishnan, Barbour, Bartolotta, Bergsson, Bhattacharjee, Buckley, Burke, Carpo, Chen, Clark, Croasdell, Crowther, Dapa, Dapa, Dayrit, de Roos, Deakin, Deng, Desai, Edwards, Ekanayaka, Eyres, Ferreyra, Fischer, Francis, Galbraith, German, Harnvoravongchai, Hinton, Huang, Hung, Hung, Immanuel, Johnson, Kabara, Katan, Kim, Kint, Kitahara, Kliewer, Liu, Louie, Lynch, Martin, Martin, May, McDonald, McEllistrem, Miller, Nakatsuji, Namkung, Nobmann, Pettit, Pizarro-Guajardo, Pruitt, Rodriguez-Palacios, Rouse, Ruhr, Ruzin, Shearer, Shilling, Smits, Sorg, Surawicz, Theinsathid, Thompson, Vardakas, Villafuerte Galvez, Wilcox, Yonezawa   +71 more
core   +1 more source

Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]

, 2020
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L., Battaglia, R., Bruno, G., Ciardi, M. R., Corazziari, E. S., de Angelis, M., Iera, J., Mascellino, M. T., Mastroianni, C. M., Miele, M. C., Morelli, S., Oliva, A., Venditti, M., Vullo, V.   +13 more
core   +1 more source