Results 81 to 90 of about 110,558 (326)

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon, Camacho-Ortiz, Adrian, Flores-Trevino, Samantha, Garza-Gonzalez, Elvira, Maldonado-Garza, Hector Jesus, Morfin-Otero, Rayo, Rodriguez-Noriega, Eduardo, Rodrıguez-Noriega, Eduardo, Tijerina-Rodrıguez, Laura, Villarreal-Trevino, Licet   +9 more
core   +1 more source

Stiffness of the C-terminal disordered linker affects the geometry of the active site in endoglucanase Cel8A [PDF]

, 2016
Cellulosomes are complex multi-enzyme machineries which efficiently degrade plant cell-wall polysaccharides. The multiple domains of the cellulosome proteins are often tethered together by intrinsically disordered regions. The properties and functions of these disordered linkers are not well understood. In this work, we study endoglucanase Cel8A, which
arxiv   +1 more source

Infection Clostridium difficile as increasing epidemiological issue

Journal of Education, Health and Sport, 2017
Introduction: Clostridium difficile as an infectious agent of pseudomembranous enterocolitis, becomes more and more frequent problem among health facilities.
Maciej Rutkowski, Anna Roszkowska, Lukasz Swierszcz, Halina Piecewicz-Szczęsna   +3 more
doaj   +3 more sources

Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report

Journal of Medical Case Reports, 2018
Background Recurrent Clostridium difficile infection is a growing problem among children due to both the increasing survival of medically fragile children with complicated chronic medical conditions resulting in prolonged antibiotic exposure and ...
D. E. Dow, P. C. Seed
doaj   +1 more source

Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium

Microorganisms, 2021
Clostridioides difficile is an anaerobic pathogen that causes significant morbidity and mortality. Understanding the mechanisms of colonization resistance against C. difficile is important for elucidating the mechanisms by which C.
Amber D. Reed, Casey M. Theriot
doaj   +1 more source

Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria [PDF]

, 2018
Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment with broad-spectrum antibiotics, is a critical precursor for ...
Baines, Simon D, Bianconi, Irene, Cutting, Simon M, Dawson, Lisa F, Harrison, Mark A, Hong, Huynh A, Kaur, Harparkash, Letertre, Marine P M, Nasher, Fauzy, Passmore, Ian J, Preston, Mark D, Swann, Jonathan R, Wren, Brendan W   +12 more
core   +5 more sources

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

Clinical Pharmacology &Therapeutics, EarlyView.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman, Ankita Narang, Ziad Al Bkhetan, Robyn L. Woods, Suzanne G. Orchard, Alice J. Owen, Michelle A. Fravel, Julia Gilmartin‐Thomas, Joanne Ryan, Peter D. Fransquet, Rory Wolfe, Chenglong Yu, John J. McNeil, Paul Lacaze, Michael E. Ernst   +14 more
wiley   +1 more source

Bayesian Decision Tree for the Classification of the Mode of Motion in Single-Molecule Trajectories [PDF]

T\"urkcan, Silvan, and Jean-Baptiste Masson. "Bayesian decision tree for the classification of the mode of motion in single-molecule trajectories." PloS one 8.12 (2013): e82799, 2015
Membrane proteins move in heterogeneous environments with spatially (sometimes temporally) varying friction and with biochemical interactions with various partners. It is important to reliably distinguish different modes of motion to improve our knowledge of the membrane architecture and to understand the nature of interactions between membrane ...
arxiv   +1 more source

Clostridium difficile infection [PDF]

, 2018
Clostridium difficile infection (CDI) refers to bacterium that infects the gut thereby causing diarrhea (Luo & Barlam, 2018). This infection is common among people who have used antibiotics for treatment.
Adamu, Jacobina A.
core   +1 more source

Dietary-based gut flora modulation against Clostridium difficile onset [PDF]

, 2007
Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Gibson, G.R., Gougoulias, C., Tuohy, K.M.   +2 more
core   +1 more source