Results 1 to 10 of about 34,415 (160)

Clostridium difficile Infection in the Elderly

Clinics in Geriatric Medicine, 2014
Clostridium difficile-associated illness is an increasingly prevalent and morbid condition. The elderly population is at a disproportionate risk of developing symptomatic disease and associated complications, including progression to severe or fulminant disease, and development of recurrent infections. This article analyzes the factors that influence C
Jonathan M, Keller, Christina M, Surawicz   +1 more
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Update on Clostridium difficile infection

Current Opinion in Gastroenterology, 2011
This review summarizes the most recent epidemiological data and advances in research into the pathogenesis, diagnosis and treatment of Clostridium difficile infection (CDI).The epidemiology of CDI has changed with the emergence of hypervirulent strains.
Caoilfhionn, O'Donoghue, Lorraine, Kyne
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Treatment of Clostridium difficile Infections

Infectious Disease Clinics of North America, 2015
Vancomycin and metronidazole were historically considered equivalent therapies for the management of Clostridium difficile infections (CDI); however, recent data confirm more favorable outcomes with vancomycin. Fidaxomicin is a narrow spectrum antibiotic that has an advantage in reducing recurrence rates compared with vancomycin, possibly owing to its ...
Melinda M, Soriano, Stuart, Johnson
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Infection control: Clostridium Difficile

Nursing and Residential Care, 2007
Clostridium difficile is a gram-positive, spore-forming bacteria that produces toxins when infection occurs. Infection can cause diarrhoea or life-threatening colitis ( Barbut et al, 2007 ). There has been an 85% reduction in hospital-acquired Clostridium difficile infections over the past eight years ( Public Health England, 2014 ).
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Clostridium difficile Infections in Children

Pediatric Infectious Disease Journal, 2009
Clostridium difficile, a spore-forming Grampositive bacillus, is a frequent cause of antibiotic-associated diarrhea and a common nosocomial pathogen. Clinical manifestations of disease range from self-limited diarrhea to life-threatening colitis and death. Historically, C.
Kristina, Bryant, L Clifford, McDonald
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Clostridium difficile infection

BMJ, 2009
Rangaiah and colleagues comment that currently used tests for Clostridium difficile toxin are not very sensitive.1 However, the specificity of these commercial assays also ranges from 97% to 99%, meaning that approximately 1-2 out of every 10 positive results using these kits are incorrect.2 False positive results are even more likely when testing ...
Mark H, Wilcox, Tim, Planche
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Treatment of clostridium difficile infection

Current Treatment Options in Gastroenterology, 2004
With the introduction of broad-spectrum antibiotics into clinical practice, Clostridium difficile infection has become the most common cause of infectious diarrhea in hospitalized patients. Although mild cases may resolve by discontinuing antibiotics, thus allowing re-establishment of colonic microflora, oral metronidazole or vancomycin is indicated if
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Clostridium difficile infection in diabetes

Diabetes Research and Clinical Practice, 2014
Diabetes-related hospitalization and hospital utilization is a serious challenge to the health care system, a situation which may be further aggravated by nosocomial Clostridium difficile (C. difficile) infection (CDI). Studies have demonstrated that diabetes increases the risk of recurrent CDI with OR (95% CI) 2.99 (1.88, 4.76). C. difficile is a gram-
Hui-Qi, Qu, Zhi-Dong, Jiang
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Clostridium difficile in paediatric infections

Journal of Infection, 1982
Summary Clostridium difficile , a major cause of antibiotic induced pseudomembranous colitis, has rarely been reported as a pathogen in paediatric patients. We report isolation of this organism from three children with various inflammatory conditions. These cases suggest that C. difficile may be pathogenic in paediatric patients.
I, Brook, G, Avery, A, Glasgow
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Update on Clostridium difficile infection

Current Gastroenterology Reports, 2000
Clostridium difficile is a major cause of antibiotic-associated diarrhea in hospital and community settings, spreading endemic and epidemic disease in developed and developing areas throughout the world. Its toxins A and B cause epithelial disruption, inflammation, and secretion. Diagnosis of infection with C. difficile is based on appropriate clinical
C S, Alcantara, R L, Guerrant
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