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Expression of Concern: Clostridium transplantifaecale sp. nov., a new bacterium isolated from patient with recurrent Clostridium difficile infection. [PDF]

New Microbes New Infect
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Therapeutics involved in managing initial and recurrent Clostridium difficile infection: An updated literature review.

World J Gastrointest Pharmacol Ther
Nagesh VK, Tran HH, Elias D, Kianifar Aguilar I, Sethi T, Menon A, Mansour C, Furman F, Tsotsos K, Subar T, Auda A, Sidiqui A, Lamar J, Wadhwani N, Dey S, Lo A, Atoot A, Weissman S, Sifuentes H, Bangolo AI.   +19 more
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Clostridium difficile Infection

Infectious Disease Clinics of North America, 2017
Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and ...
Luis, Alcalá Hernández, Elena, Reigadas Ramírez, Emilio, Bouza Santiago   +2 more
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Clostridium difficile Infection

Critical Reviews in Clinical Laboratory Sciences, 1996
The spore-forming anaerobe Clostridium difficile has become a serious enteropathogen. Changes in the composition of natural intestinal flora, mainly due to antibiotic therapy, permit its colonization of, and multiplication in, the colon. The disease is caused by (entero)toxin A and (cyto)toxin B, and infection ranges from asymptomatic carrier state and
Dieter H. M. Gröschel, B. Toye
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Clostridium difficileInfection

New England Journal of Medicine, 2015
This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this nosocomial and potentially fatal infectious diarrhea, as well as the associated risk factors. New treatments include fecal microbiota transplantation for disease that is resistant to vancomycin.
Sam K, Sharma, Kentaro, Nakajima, Parul J, Shukla   +2 more
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Clostridium difficile infection

BMJ, 2009
Rangaiah and colleagues comment that currently used tests for Clostridium difficile toxin are not very sensitive.1 However, the specificity of these commercial assays also ranges from 97% to 99%, meaning that approximately 1-2 out of every 10 positive results using these kits are incorrect.2 False positive results are even more likely when testing ...
Mark H, Wilcox, Tim, Planche
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Clostridium difficile Infection

Annual Review of Medicine, 1998
Clostridium difficile infection is associated with broad-spectrum antibiotic therapy and is the most common cause of infectious diarrhea in hospital patients. Pathogenic strains of C. difficile produce two protein exotoxins, toxin A and toxin B, which cause colonic mucosal injury and inflammation. Infection may be asymptomatic, cause mild diarrhea, or
C P, Kelly, J T, LaMont
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Infection control: Clostridium Difficile

Nursing and Residential Care, 2007
Clostridium difficile is a gram-positive, spore-forming bacteria that produces toxins when infection occurs. Infection can cause diarrhoea or life-threatening colitis ( Barbut et al, 2007 ). There has been an 85% reduction in hospital-acquired Clostridium difficile infections over the past eight years ( Public Health England, 2014 ).
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Clostridium difficile infection: new developments in epidemiology and pathogenesis

Nature Reviews Microbiology, 2009
M. Rupnik, M. Wilcox, D. Gerding
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