Results 261 to 270 of about 3,472,654 (379)

Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings, Serbülent Ünsal, Mathieu Rappas, Matthew Barnes, Maria Waldhoer, Ben Holland, Martin Culka   +6 more
wiley   +1 more source

Isolation, toxin gene profiling, and phylogenetic analysis of Clostridium perfringens in Egyptian fruit bats: public health and epidemiological implications. [PDF]

Sci Rep
Allam TA, Abdel-Kader F, Kadry M.
europepmc   +1 more source

Rapid and accurate diagnosis of Clostridium difficile infection by real-time polymerase chain reaction [PDF]

, 2018
Pil Hun Song, Jung Hwa Min, You Sun Kim, Soo Yeon Jo, Eun Jin Kim, Kyung Jin Lee, Jeong‐Hun Lee, Hyun Jung Sung, Jeong Seop Moon, Dong Hee Whang   +9 more
openalex   +1 more source

The Changing Epidemiology of Clostridium difficile Infections

Clinical Microbiology Reviews, 2010
J. Freeman, M. Bauer, Simon D Baines, J. Corver, W. Fawley, B. Goorhuis, E. Kuijper, M. Wilcox   +7 more
semanticscholar   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source

The Emerging Role of Dietary Bacteriophage in Monogastric Animals in the Post-Antibiotic Era-A Review. [PDF]

Vet Sci
Sampath V, Kim NG, Kim IH.
europepmc   +1 more source

Integrating Transcriptomics and Gut Microbiota Analysis Reveals the Anti‐Osteoporotic Mechanisms of Wine and Oil Co‐Processed Epimedium

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Firstly, we determined the content of the components in the co‐products of Epimedium wine and oil. Secondly, the clinical indications of the co‐products of Epimedium wine and oil were determined by in vitro cell experiments. Finally, the in vivo animal model was used for experimental verification.
Jinling Liang, Shichang Li, Yulin Dai, Zifeng Pi, Jia Liu, Pan Li, Weixia Sun, Tao Jiang, Tianyang Xu, Peng Yu   +9 more
wiley   +1 more source

Lignocellulose degradation capabilities and distribution of antibiotic resistance genes and virulence factors in Clostridium from the gut of giant pandas. [PDF]

Commun Biol
Deng W, Li C, Huang Y, Liu C, Li R, Li T, Wu D, He Y, Li D, Yang S, Zou L, Zhao K.   +11 more
europepmc   +1 more source

The membrane as a target for controlling hypervirulent Clostridium difficile infections.

Journal of Antimicrobial Chemotherapy, 2013
Xiaoqian Wu, Philip T. Cherian, Richard E. Lee, J. Hurdle   +3 more
semanticscholar   +1 more source

Effects of Defined Pig Microbiota on Acute Salmonellosis in Gnotobiotic Piglets

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Germ‐free piglets lack protective microbiota and are highly vulnerable to Salmonella Typhimurium LT2 infection. Pre‐colonization with defined pig microbiota supports early immune response and intestinal barrier maturation. By measuring pathogen spread, intestinal structure, goblet cell density, cytokines, and tight‐junction markers with molecular and ...
Igor Splichal, Katerina Polakova, Marek Sinkora, Vera Neuzil Bunesova, Nikol Modrackova, Eva Vlkova, Zdislava Kindlova, Kristyna Horvathova, Alla Splichalova   +8 more
wiley   +1 more source