Results 131 to 140 of about 802 (167)
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Interactions Between Clostridium perfringens Enterotoxin and Claudins
2011Clostridium perfringens enterotoxin (CPE), a single polypeptide of approximately 35 kDa in size, is -associated with type A food poisoning and such non-foodborne gastrointestinal diseases as antibiotic-associated diarrhea and sporadic diarrhea. CPE action begins with binding of the toxin to a claudin -receptor, forming a ∼90 kDa small complex that then
Susan L, Robertson, Bruce A, McClane
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An investigation into Clostridium perfringens enterotoxin-associated diarrhoea
Journal of Hospital Infection, 1991An investigation was carried out to establish the incidence of diarrhoea associated with the presence of enterotoxigenic Clostridium perfringens. The results indicate a high risk group, namely elderly hospitalized patients, who should be investigated for this organism in a similar way to Clostridium difficile if symptoms occur.
S C, Samuel, P, Hancock, D A, Leigh
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Veterinary Microbiology, 2014
Clostridium perfringens has been suspected as an enteropathogen in dogs. However, its exact role in gastrointestinal (GI) disorders in dogs remains unknown. Recent studies suggest the importance of an altered intestinal microbiota in the activation of virulence factors of enteropathogens.
Yasushi Minamoto +4 more
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Clostridium perfringens has been suspected as an enteropathogen in dogs. However, its exact role in gastrointestinal (GI) disorders in dogs remains unknown. Recent studies suggest the importance of an altered intestinal microbiota in the activation of virulence factors of enteropathogens.
Yasushi Minamoto +4 more
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The molecular mode of action of Clostridium perfringens enterotoxin
The American Journal of Clinical Nutrition, 1979While certain strains of Clostridium perfringens have been associated with food poisoning outbreaks for the past 30 years, it has been only during the past 10 years that progress has been made in describing the disease process. And only within the past 5 years has meaningful progress been made in understanding the mechanism by which the disease is ...
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Trypsinization of derivatives of Clostridium perfringens enterotoxin
Letters in Applied Microbiology, 1986Three proteins, named P1, P2 and P3, were separated from purified Clostridium perfringens enterotoxin by high performance liquid chromatography (HPLC) on a DEAE-5PW column. The relative biological activities of P1, P2 and P3 on protein basis determined by the African green monkey kidney (Vero) cell staining assay were 3·0, 1·9 and 1·0, respectively. P1,
T. UEMURA +3 more
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Human Disease Associated with Clostridium perfringens Enterotoxin
1997Clostridium perfringens continues to be a common cause of food-borne disease. Characteristics of this organism that contribute to its ability to cause food-borne illness include the formation of heat-resistant spores that survive normal cooking/heating temperatures, a rapid growth rate in warm food, and the production of enterotoxin (CPE) in the human ...
R R, Meer, J G, Songer, D L, Park
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Chymotrypsin treatment increases the activity of Clostridium perfringens enterotoxin
Toxicon, 1991Chymotrypsin treatment of the enterotoxin from Clostridium perfringens results in the loss of 36 amino acids from the N-terminus and 3 amino acids from the C-terminus. This processing results in a 3.2 fold increase in activity on Vero cells, which is close to what had been found for trypsin treatment following the loss of 25 amino acids from the N ...
P E, Granum, M, Richardson
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Clostridium Perfringens Enterotoxin-Associated Diarrhoea
1987Enterotoxigenic strains of C. perfringens are now implicated in cases of diarrhoea other than food poisoning. There is good evidence that cross-infection may occur and that cross-infection control measures are helpful in limiting spread of the disease.
S. P. Borriello +3 more
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Molecular Biology of Clostridium perfringens Enterotoxin
1993Clostridium perfringens is a large, gram-positive, spore-forming, anaerobic and nonmotile rod belonging to the family Bacillaceae. It is a common inhabitant of the soil and plays an important part in the putrefication process. C. perfringens is also readily isolated from dust, raw meat, water, and the intestinal tract of man and animals, and is the ...
Per Einar Granum +1 more
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The role of enterotoxin in Clostridium perfringens type A enteritis
Canadian Journal of Microbiology, 1971Vegetative cells of three strains of Clostridium perfringens type A, free of erythemal activity, were suspended in fresh medium and injected into ligated intestinal loops of lambs. Examination of the loop contents after 6.5 h showed significant accumulation of fluid, multiplication and sporulation of C.
A H, Hauschild, L, Niilo, W J, Dorward
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