Results 51 to 60 of about 4,169 (203)

Prevention Of Swarming Of Clostridium Septicum [PDF]

Journal of Medical Microbiology, 1972
Summary A CI. septicum O antiserum, prepared in the rabbit against the two serological groups of Moussa, inhibits the swarming growth of CI. septicum in plate cultures. Advantage may be taken of this in the separation of other organisms from mixtures with CI. septicum and in performing surface viable counts with CI. septicum.
A T, Willis, K, Williams
openaire   +2 more sources

A toxin hunter in the microworld of bacteria: a project on novel inhibitors against bacterial AB5 toxins [PDF]

, 2016
[要旨] 病原性細菌が産生する蛋白性のAB5型トキシンは1個のAサブユニットと5個のBサブユニットから構成される外毒素である。両サブユニットはそれぞれ特徴的な役割を持ち，互いに巧妙に機能分担をして一つのトキシンを形成している。Aサブユニットは主に毒性に直接関与する特異的な酵素活性を有する。一方，Bサブユニットは標的細胞のレセプターに対する結合能を有し，AB5型トキシンを標的細胞に吸着させる。ここでは毒性が全く異なるAB5型トキシンとして，コレラ菌が産生するコレラトキシン（CT ...
Fujun Shen (314092), Jiandong Yang (196004), Rong Hou (149003), Yang Da (89805)   +3 more
core   +3 more sources

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

A Systematic Review of Cases of Meningitis in the Absence of Cerebrospinal Fluid Pleocytosis on Lumbar Puncture [PDF]

, 2019
Background: Definitive diagnosis of meningitis is made by analysis of cerebrospinal fluid (CSF) culture or polymerase chain reaction (PCR) obtained from a lumbar puncture (LP), which may take days.
Pettigrew, Alexis, Troendle, Michelle
core   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, Volume 2, Issue 3, September 2025.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Clostridium septicum: An Unusual Link to a Lower Gastrointestinal Bleed

Case Reports in Gastroenterology, 2016
Clostridium septicum is a highly virulent pathogen which is associated with colorectal malignancy, hematological malignancy, immunosuppression, diabetes mellitus and cyclical neutropenia. Presentation may include disseminated clostridial infection in the
Kegan Jessamy, Fidelis O. Ojevwe, Ezinnaya Ubagharaji, Anuj Sharma, Obiajulu Anozie, Christy Ann Gilman, Sekou Rawlins   +6 more
doaj   +1 more source

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein [PDF]

, 2016
Lysenin from the coelomic fluid of the earthworm Eisenia fetida belongs to the aerolysin family of small β-pore-forming toxins (β-PFTs), some members of which are pathogenic to humans and animals. Despite efforts, a high-resolution structure of a channel
A Yamaji, AR Cole, BR Sellman, C Xu, CG Savva, DC Briggs, FW Studier, G Tang, G Trinquier, GE Schulz, GN Murshudov, H Bruhn, H Kobayashi, I Iacovache, I Iacovache, J Ballard, JM Alam, JM Mancheno, K Kwiatkowska, K Yamashita, K Zhang, L De Colibus, L Song, L Swint-Kruse, M Herec, MT Degiacomi, MW Parker, N Yilmaz, N Yilmaz, P Emsley, P Leone, P Szczesny, R Olson, RA Nicholls, RS Pantelic, S De, S Miyata, SH Scheres, SH Scheres, SH Scheres, T Akiba, T Akiba, WC Wimley, X Li, XX Yan, Y Sekizawa, Y Sekizawa   +46 more
core   +1 more source

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

International Journal of Cancer, Volume 157, Issue 4, Page 599-613, 15 August 2025.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder, Amee R. Manges, Rachel A. Murphy   +2 more
wiley   +1 more source

Clostridium septicum growth from a total knee arthroplasty associated with intestinal malignancy: a case report

BMC Infectious Diseases, 2012
Background Previous reports of infection with Clostridium septicum have identified an unexpected association with concurrent malignancy. The reported rate of associated malignancy has been found to be as high as 81 percent.
Economedes Demetri M, Santoro Jerome, Deirmengian Carl A   +2 more
doaj   +1 more source

Diagnosis and successful treatment of open pyometra in a wild European brown hare (Lepus europaeus)

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract This case report describes an open pyometra in a wild adult female hare (Lepus europaeus) that was rescued in the Umbria countryside (Italy) during mid‐January. The clinical signs observed included anorexia and a mucopurulent to haemorrhagic discharge from the vulva.
Claudia Massone, Oriana Cianca, Isabella Costantino, Daniele Marini, Domenico Caivano   +4 more
wiley   +1 more source