Results 1 to 10 of about 92,926 (248)

Comparative pathogenomics of Clostridium tetani. [PDF]

PLoS One, 2017
Clostridium tetani and Clostridium botulinum produce two of the most potent neurotoxins known, tetanus neurotoxin and botulinum neurotoxin, respectively. Extensive biochemical and genetic investigation has been devoted to identifying and characterizing various C. botulinum strains. Less effort has been focused on studying C.
Cohen JE, Wang R, Shen RF, Wu WW, Keller JE.   +4 more
europepmc   +7 more sources

An Assessment of the Presence of Clostridium tetani in the Soil and on Other Surfaces. [PDF]

West J Emerg Med
Introduction: Standard emergency medicine practice includes tetanus vaccine administration as part of wound care management for patients who are not fully immunized.
Shalaby M, Catenazzi A, Smith MF, Farrow Ii RA, Farcy D, Mechanic O, Zitek T.   +6 more
europepmc   +6 more sources

Genome of a chronic osteitis-causing Clostridium tetani. [PDF]

New Microbes New Infect, 2014
We sequenced the genome of a Clostridium tetani strain that caused chronic tibial osteitis without any clinical sign of tetanus in a 26-year-old man previously vaccinated against this disease. The genome contained a plasmid that harboured the tetX-tetR tetanospasmin operon, and was highly similar to that of a tetanus-causing strain.
Fournier PE, Levy PY, Million M, Croce O, Blanc-Tailleur C, Brouqui P, Raoult D.   +6 more
europepmc   +6 more sources

Clostridium tetani osteitis without tetanus. [PDF]

Emerg Infect Dis, 2014
To the Editor: Posttraumatic osteoarticular infections caused by Clostridium spp. are rare, and their outcomes are often unfavorable because of the persistence of the bacteria in bone (1,2). In a recent series of 12 patients (2), only 1 case of posttraumatic osteoarticular infection was caused by C.
Levy PY, Fournier PE, Lotte L, Million M, Brouqui P, Raoult D.   +5 more
europepmc   +5 more sources

Humoral Immunity to Measles, Mumps, Rubella, Diphtheria, Tetanus and Pertussis After Cancer Treatment in Children. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Treatment for pediatric malignancies has distinct effects on the immune system. Aims Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.
Sundell S, Laine M, Järvelä L, Peltola V, Vuorinen T, Lähteenmäki P, Schuez-Havupalo L.   +6 more
europepmc   +2 more sources

Clostridium tetani bacteraemia [PDF]

Journal of Medical Microbiology, 2013
Tetanus is a neuromuscular disease in which Clostridium tetani exotoxin (tetanospasmin) produces muscle spasms, incapacitating its host. To our knowledge, C. tetani bacteraemia has never been reported in the literature. The ideal management of this entity remains unresolved given that there is no literature to guide the therapy.
Muhammad Afridi, Jack Boghossian, Raymund Sison, Rabih Hallit, Elie Salem, Jihad Slim   +5 more
openaire   +4 more sources

Equine Blood Microbiome in a Cohort of Clinically Healthy Trail Riding Horses. [PDF]

J Vet Intern Med
ABSTRACT Background Emerging research suggests the presence of a blood microbiome in clinically healthy individuals. Characterizing bacterial composition and abundance in blood from a group of healthy horses is of clinical interest. Hypothesis/Objectives Horses in a closed herd environment will have blood microbiomes with similarities among individuals.
Simms N, Bertone JJ, Melgarejo T, O'Shea C, Linde A.   +4 more
europepmc   +2 more sources

Genomics of Clostridium tetani [PDF]

Research in Microbiology, 2015
Genomic information about Clostridium tetani, the causative agent of the tetanus disease, is scarce. The genome of strain E88, a strain used in vaccine production, was sequenced about 10 years ago. One additional genome (strain 12124569) has recently been released. Here we report three new genomes of C.
Holger Brüggemann, Elzbieta Brzuszkiewicz, Diana Chapeton-Montes, Lucile Plourde, Denis Speck, Michel R. Popoff   +5 more
openaire   +5 more sources

The Germination of Spores of Clostridium tetani [PDF]

Journal of General Microbiology, 1972
SUMMARY: The spores of Clostridium tetani will germinate aerobically and anaerobically in complex media such as heart infusion broth or tryptone with yeast extract at 37° and pH 7.5. A synthetic medium as effective as heart infusion broth for germination under both aerobic and anaerobic conditions consists of 1 mM-methionine, 100 mM-lactate, 82 μM ...
K. T. Holland, J. G. Shoesmith
openaire   +3 more sources

Regulation of toxin synthesis in Clostridium botulinum and Clostridium tetani [PDF]

Toxicon, 2013
Botulinum and tetanus neurotoxins are structurally and functionally related proteins that are potent inhibitors of neuroexocytosis. Botulinum neurotoxin (BoNT) associates with non-toxic proteins (ANTPs) to form complexes of various sizes, whereas tetanus toxin (TeNT) does not form any complex.
Connan, Chloé, Denève, Cécile, Mazuet, Christelle, Popoff, Michel,   +3 more
openaire   +5 more sources