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Autism and clostridium tetani

Medical Hypotheses, 1998
Autism is a severe developmental disability believed to have multiple etiologies. This paper outlines the possibility of a subacute, chronic tetanus infection of the intestinal tract as the underlying cause for symptoms of autism observed in some individuals. A significant percentage of individuals with autism have a history of extensive antibiotic use.
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Inducible Lysis inClostridium tetani

Journal of Bacteriology, 1967
Lysis was induced in seven strains ofClostridium tetaniby exposure to mitomycin C. The search for a suitable indicator strain to detect bacteriophage in lysates has, so far, been unsuccessful. Inhibition studies on macromolecular synthesis during induction have shown that deoxyribonucleic acid, ribonucleic acid, and protein syntheses are all involved ...
Lawrence M. Prescott   +1 more
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Tetanus (Clostridium tetani)

2021
Tetanus (lockjaw) is a serious bacterial infection caused by Clostridium tetani which produce a neurotoxin that affects the brain and nervous system. Individual cases of the disease have been reported in camels in some countries. Clinical signs started with a stiff gate, an extension of the neck, frothy salivation, refusal to feed, and swelling of the ...
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Clostridium tetani

2002
Publisher Summary Tetanus was first recorded in the very earliest medical literature. The most common form of the disease is generalized tetanus, in which the portal of entry is a minor wound in 80% of cases. It usually begins with a characteristic facial trismus.
Cesare Montecucco   +2 more
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Growth of Clostridium tetani in vivo

1975
Under favourable conditions tetanus spores may germinate and multiply in vivo soon after their introduction into the tissues. Dorothy Russel [3] found that vegetation was visible microscopically on the second day in necrotic foci produced in guinea-pigs by the injection of earth. In lesions produced by 5% calcium chloride solution considerable vegation
A. G. MacIver, J. W. G. Smith
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Adjuvants for Clostridium tetani and Clostridium diphtheriae vaccines updating

Human Antibodies, 2017
It's known that diphtheria and tetanus are a contagious lethal diseases over the years, they caused by pathogenic microbes corynebacterium diphtheria and Clostridium tetani, respectively. The diseases result from the production of bacterial toxin. Vaccination with bacterial toxoid vaccines adsorbed on particulates adjuvants still are the best way to ...
Elrashdy M. Redwan   +3 more
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Serologic Types of Clostridium Tetani

Journal of Infectious Diseases, 1928
Based on the specificity of the agglutination reaction numerous microbic species have been differentiated into various types or groups. While the clinical picture of the disease caused by the different types of a given bacterial species may be the same, or very similar, this differentiation of the causative organism into types has been of inestimable ...
Janet B. Gunnison, George E. Coleman
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Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani

Anaerobe, 2004
Botulinum and tetanus neurotoxins are structurally and functionally related 150 kDa proteins that are potent inhibitors of neuroexocytosis. Botulinum neurotoxin associates with non-toxic proteins to form complexes of various sizes. The botulinum neurotoxin and non-toxic protein genes are clustered in a DNA segment called the botulinum locus. This locus
Raffestin, Stephanie   +4 more
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