Results 11 to 20 of about 26,456 (206)

More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines [PDF]

Proteomes, 2019
Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C.
Jens Möller, Max Edmund Kraner, Andreas Burkovski   +2 more
doaj   +2 more sources

Generalized Tetanus Associated With Malaria and Probable Meningitis in a 4-Year-Old Patient: A Case Report in Limbe Regional Hospital, Cameroon. [PDF]

Clin Case Rep
ABSTRACT Tetanus is a life‐threatening disease preventable by immunization through vaccines. In resource‐limited settings, its association with other acute infections should be managed cautiously. A 4‐year‐old unvaccinated male was referred from a nearby hospital for better management of severe malaria and probable enteric fever, after presenting there
Tchuisseu Ngapjang CD, Fotso C, Gobina R, Lingo PA, Shumbang Tchumukong QJ, Kouam BB, Effila M, Berinyuy Nyuydzefon E, Vincent Siysi V.   +8 more
europepmc   +2 more sources

Genomics of Clostridium tetani [PDF]

Research in Microbiology, 2015
Genomic information about Clostridium tetani, the causative agent of the tetanus disease, is scarce. The genome of strain E88, a strain used in vaccine production, was sequenced about 10 years ago. One additional genome (strain 12124569) has recently been released. Here we report three new genomes of C.
Brüggemann, Holger, Brzuszkiewicz, Elzbieta, Chapetón-Montes, Diana, Plourde, Lucile, Speck, Denis, Popoff, Michel   +5 more
openaire   +4 more sources

Clostridium tetani bacteraemia [PDF]

Journal of Medical Microbiology, 2013
Tetanus is a neuromuscular disease in which Clostridium tetani exotoxin (tetanospasmin) produces muscle spasms, incapacitating its host. To our knowledge, C. tetani bacteraemia has never been reported in the literature. The ideal management of this entity remains unresolved given that there is no literature to guide the therapy.
Muhammad Afridi, Jack Boghossian, Raymund Sison, Rabih Hallit, Elie Salem, Jihad Slim   +5 more
openaire   +3 more sources

Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains

Nature Communications, 2023
The analysis of microbial genomes from human archaeological samples offers a historic snapshot of ancient pathogens and provides insights into the origins of modern infectious diseases.
Harold P. Hodgins, Pengsheng Chen, Briallen Lobb, Xin Wei, Benjamin J. M. Tremblay, Michael J. Mansfield, Victoria C. Y. Lee, Pyung-Gang Lee, Jeffrey Coffin, Ana T. Duggan, Alexis E. Dolphin, Gabriel Renaud, Min Dong, Andrew C. Doxey   +13 more
doaj   +1 more source

Microwave assisted synthesis of novel 4h-chromene derivatives bearing phenoxypyrazole and their antimicrobial activity assess [PDF]

Journal of the Serbian Chemical Society, 2012
A new series of 4H-chromene derivatives 4(a-p) bearing 5-phenoxypyrazole nucleus has been synthesized under microwave irradiation by reaction of 5-phenoxypyrazole-4-carbaldehyde 1(a-h), malononitrile 2 and compounds (Cyclohexanedione, Dimedon) 3(a-b ...
Sangani Chetan B., Shah Nimesh M., Patel Manish P., Patel Ranjan G.   +3 more
doaj   +1 more source

The Germination of Spores of Clostridium tetani [PDF]

Journal of General Microbiology, 1972
SUMMARY: The spores of Clostridium tetani will germinate aerobically and anaerobically in complex media such as heart infusion broth or tryptone with yeast extract at 37° and pH 7.5. A synthetic medium as effective as heart infusion broth for germination under both aerobic and anaerobic conditions consists of 1 mM-methionine, 100 mM-lactate, 82 μM ...
K. T. Holland, J. G. Shoesmith
openaire   +3 more sources

Clinical Profile, Management and Outcome in Paediatric Patients with Tetanus: A Case Series [PDF]

Journal of Clinical and Diagnostic Research, 2023
Tetanus is an acute infectious disease, caused by spores of the bacterium Clostridium tetani. The spores are found everywhere in the environment, particularly in soil, ash, intestinal tracts/faeces of animals and humans, on the surfaces of skin and rusty
Arpita Manish Patel, Dhruti Manish Pandya, Kamleshkumar G Rathod, Ketan D Gadhavi, Bharat Muliya   +4 more
doaj   +1 more source

Tetanus as Cause of Mass Die-off of Captive Japanese Macaques, Japan, 2008

Emerging Infectious Diseases, 2012
In 2008 in Japan, 15/60 captive Japanese macaques died. Clostridium tetani was isolated from 1 monkey, and 11 had tetanus-specific symptoms. We conclude the outbreak resulted from severe environmental C. tetani contamination.
Tomomi Nakano, Shin-ichi Nakamura, Akihiko Yamamoto, Motohide Takahashi, Yumi Une   +4 more
doaj   +1 more source

Isolation of Bacteriophage for Clostridium tetani [PDF]

Journal of Virology, 1969
The purpose of this report is to note the isolation of a Clostridium tetani phage from soil and to specify the procedure used to obtain suitable lawns for plaque formation.
Diane Roseman, Robert L. Richardson
openaire   +3 more sources