Structural and functional analysis of hypothetical and conserved proteins of Clostridium tetani
Summary: The progress in biological technologies has led to rapid accumulation of microbial genomic sequences with a vast number of uncharacterized genes. Proteins encoded by these genes are usually uncharacterized, hypothetical, and/or conserved.
Shymaa Enany
doaj +1 more source
Regulation of toxin synthesis in Clostridium botulinum and Clostridium tetani [PDF]
Botulinum and tetanus neurotoxins are structurally and functionally related proteins that are potent inhibitors of neuroexocytosis. Botulinum neurotoxin (BoNT) associates with non-toxic proteins (ANTPs) to form complexes of various sizes, whereas tetanus toxin (TeNT) does not form any complex.
Connan, Chloé +3 more
openaire +3 more sources
Summary: Tetanus resulting from ear injury remains an important health problem, particularly in the developing world. We report the successful detection of Clostridium tetani using tetX specific primers targeting the Cl. tetani neurotoxin. The sample was
Madhu Ganesh +5 more
doaj +1 more source
Humoral Immunity to Measles, Mumps, Rubella, Diphtheria, Tetanus and Pertussis After Cancer Treatment in Children. [PDF]
ABSTRACT Background Treatment for pediatric malignancies has distinct effects on the immune system. Aims Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.
Sundell S +6 more
europepmc +2 more sources
A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]
Peer reviewedPublisher ...
Altschul +48 more
core +1 more source
Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]
Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L +10 more
core +7 more sources
The Sporulation of Clostridium tetani [PDF]
SUMMARY: In the sporulation of Clostridium tetani, a rod-like fusion nucleus is formed from the two nuclear units typical of a ‘smooth’ bacillus. The fusion nucleus divides into two smaller rods, one of which degenerates; the other is included in the spore.
openaire +3 more sources
Generalized tetanus: clinical case report and review of the literature [PDF]
Indexación: Web of Science; ScieloIntroducción: El tétanos es una enfermedad grave y potencialmente mortal, que afecta al sistema nervioso y causada por la bacteria Clostridium tetani.
Armijo M., José +2 more
core +1 more source
A universal strategy for high-yield production of soluble and functional clostridial collagenases in E. coli [PDF]
Clostridial collagenases are foe and friend: on the one hand, these enzymes enable host infiltration and colonization by pathogenic clostridia, and on the other hand, they are valuable biotechnological tools due to their capacity to degrade various types
Dorota Nüss +6 more
core +2 more sources
Taxonomy of Clostridium tetani and Related Species [PDF]
Clostridium tetani and its related species C. tetanomorphum, C. cochlearium and C. lentoputrescens were examined for DNA-DNA homology and biochemical properties. Two distinctly different groups were included under the name of C. tetanomorphum: one was identical with C. cochlearium and the name C.
Imiko Okado +3 more
openaire +3 more sources

