Results 81 to 90 of about 448,002 (267)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FUZZY CLOSURE SYSTEMS AND FUZZY CLOSURE OPERATORS
Communications of the Korean Mathematical Society, 2004 Summary: We introduce fuzzy closure systems and fuzzy closure operators as extensions of closure systems and closure operators. We study relationships between fuzzy closure systems and fuzzy closure spaces. In particular, two families \(F(S)\) and \(F(C)\) of fuzzy closure systems and fuzzy closure operators on \(X\) are complete lattice isomorphic.
Kim, Yong Chan, Ko, Jung Mi
openaire +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Tight closure, plus closure and Frobenius closure in cubical cones [PDF]
Transactions of the American Mathematical Society, 1999 This is a detailed analysis of tight closure, plus closure, Frobenius closure, and irreducibility of ideals in the ring \(R = K[[X,Y,Z]]/(X^3 + Y^3 + Z^3)\), where \(K\) is a field of characteristic \(p\) and \(p \not = 3\). The author uses the \(\mathbb{Z}_3\)-grading on this ring, and proves more generally that the tight closure of a homogeneous ...
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Graphs and Combinatorics, 2000 As the title indicates, this is a survey of results involving various types of closure conditions, where closure conditions involve adding an edge to a graph without changing the existence of some specified graphical property. Most of the graphical properties studied are hamiltonian type properties such as hamiltonian, panconnected, pancyclic, and ...
Broersma, Hajo +2 more
openaire +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
La fin de Lost, le paradoxe des séries et l’expérience de la perte
TV Series, 2016 That the viewers of the Lost TV series were so disappointed by its last episode has something to do with the philosophical problem of narrative closure.
Hugo Clémot
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source