Results 101 to 110 of about 1,865,587 (341)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Reasoning about exceptions in ontologies: from the lexicographic closure to the skeptical closure

open access: yes, 2018
Reasoning about exceptions in ontologies is nowadays one of the challenges the description logics community is facing. The paper describes a preferential approach for dealing with exceptions in Description Logics, based on the rational closure.
Giordano, Laura, Gliozzi, Valentina
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

La fin de Lost, le paradoxe des séries et l’expérience de la perte

open access: yesTV Series, 2016
That the viewers of the Lost TV series were so disappointed by its last episode has something to do with the philosophical problem of narrative closure.
Hugo Clémot
doaj   +1 more source

Evaluation of Bladed Skid Trail Closure Methods in the Ridge and Valley Region [PDF]

open access: bronze, 2017
Joseph Andrew Vinson   +3 more
openalex   +1 more source

A study of fatigue crack closure using electric potential and compliance techniques [PDF]

open access: yes
Compared are closure data produced on the same specimen by the crack tip compliance gage and electric potential techniques. Experiments on 7075-T651 aluminum center cracked panels produced equivalent results on closure using the two techniques.
Cassatt, G. C., Clarke, C. K.
core   +1 more source

Closure systems and closure hypergroups

open access: yesRatio Mathematica, 1999
Given a closure system, a hyperoperation is defined by setting as hyperproduct of two elements the minimum element containing them. Some properties on the topic are proved, and the concept of a closure hypergroup is defined.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The place of spermatic fascia closure during open herniotomy in male children

open access: yesNigerian Journal of Surgery, 2013
Introduction: There is currently no consensus about closing or otherwise of the spermatic fascia at herniotomy in children. This stems from lack of evidence to justify either stand, and most literatures are silent on this.
Philemon E Okoro, Isesoma Gbobo
doaj   +1 more source

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