Results 81 to 90 of about 462,658 (268)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
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Sillages Critiques, 2018 This essay examines the ways in which metaphysical detective stories subvert one of detective fiction’s most emblematic features: the investigation’s resolution and the subsequent narrative closure. In the “The Man of the Crowd” (1840), the father of the
Antoine Dechêne
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Closure systems and closure hypergroups
Ratio Mathematica, 1999 Given a closure system, a hyperoperation is defined by setting as hyperproduct of two elements the minimum element containing them. Some properties on the topic are proved, and the concept of a closure hypergroup is defined.
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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Известия Иркутского государственного университета: Серия "Математика", 2019 Multioperations are operations from a finite set A to set of all subsets of A. The usual composition operator leads to a continuum of closed sets. Therefore, the research of closure operators, which contain composition and other operations becomes ...
V.I. Panteleev, L. Riabets
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Closure and Happy Endings in Janet Frame’s The Lagoon and Other Stories
Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2013 Closure and happy endings are not phrases that immediately come to mind when looking at Janet Frame’s stories in her first collection The Lagoon and Other Stories (1951), texts marked by low narrative content and inconclusiveness which nevertheless ...
Armelle Parey
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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