Results 121 to 130 of about 759,634 (294)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Quasi-uniform and syntopogenous structures on categories [PDF]

open access: yes, 2019
Philosophiae Doctor - PhDIn a category C with a proper (E; M)-factorization system for morphisms, we further investigate categorical topogenous structures and demonstrate their prominent role played in providing a uni ed approach to the theory of ...
Iragi, Minani
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

On the Closure Operator and the Closure System of Many Sorted Sets

open access: yes, 2008
Summary. In this paper definitions of many sorted closure system and many sorted closure operator are introduced. These notations are also introduced in [11], but in another meaning.

core  

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Closures and generating sets related to combinations of structures

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2016
We investigate closure operators and describe their properties for $E$-combinations and $P$-combinations of structures and their theories including the negation of finite character and the exchange property.
S. Sudoplatov
doaj  

Greedoids and Violator Spaces

open access: yesAxioms
This research explores the interplay between violator spaces and greedoids—two distinct theoretical frameworks developed independently. Violator spaces were introduced as a generalization of linear programming, while greedoids were designed to ...
Yulia Kempner, Vadim E. Levit
doaj   +1 more source

On the closure operator and the closure system of many sorted sets

open access: yes, 1996
Summary. In this paper definitions of many sorted closure system and many sorted closure operator are introduced. These notations are also introduced in [9], but in another meaning.
Artur Korniłowicz
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Going down in (semi)lattices of finite Moore families and convex geometries [PDF]

open access: yes
In this paper we first study the changes occuring in the posets of irreducible elements when one goes from an arbitrary Moore family (respectively, a convex geometry) to one of its lower covers in the lattice of all Moore families (respectively, in the ...
Gabriela Bordalo   +2 more
core  

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