Results 121 to 130 of about 797,892 (301)

Closure operators in the category of quandles

open access: yes, 2016
We study a regular closure operator in the category of quandles. We show that the regular closure operator and the pullback closure operator corresponding to the reflector from the category of quandles to its full subcategory of trivial quandles coincide,
Even, Valérian, Gran, Marino
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Greedoids and Violator Spaces

open access: yesAxioms
This research explores the interplay between violator spaces and greedoids—two distinct theoretical frameworks developed independently. Violator spaces were introduced as a generalization of linear programming, while greedoids were designed to ...
Yulia Kempner, Vadim E. Levit
doaj   +1 more source

Closure operator constructions depending on one parameter

open access: yes, 2003
Let X be an (E, M)-category for sinks. For each subclass N of M, two new Galois connections that generalize the Clementino-Tholen connectedness and separation Galois connections are introduced.
Castellini G., Holgate D.
core  

Amplatzer device closure of an inferior venosus atrial septal defect after surgical closure of a secundum atrial septal defect [PDF]

open access: yes, 2004
This article presents a patient who had transcatheter closure of a low atrial septal defect which was overlooked during surgical closure of a secundum atrial septal defect.
DeGiovanni, Joseph V.   +2 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Some order dualities in logic, games and choices [PDF]

open access: yes
We first present the concept of duality appearing in order theory, i.e. the notions of dual isomorphism and of Galois connection. Then, we describe two fundamental dualities, the duality extension/intention associated with a binary relation between two ...
Bernard Monjardet
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Closures and generating sets related to combinations of structures

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2016
We investigate closure operators and describe their properties for $E$-combinations and $P$-combinations of structures and their theories including the negation of finite character and the exchange property.
S. Sudoplatov
doaj  

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