Results 101 to 110 of about 797,892 (301)

On the Closure Operator and the Closure System of Many Sorted Sets

open access: yes, 2008
Summary. In this paper definitions of many sorted closure system and many sorted closure operator are introduced. These notations are also introduced in [11], but in another meaning.

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Some properties of sg-submaximal in minimal structure space [PDF]

open access: yesWarasan Witthayasat Lae Theknoloyi Mahawitthayalai Mahasarakham, 2019
In this paper, we study the properties of open sets, closed sets, closure operator and interior operator on minimal structure space. We will provide characterization of sg -submaximal space by using various kinds of generalized closed sets and open sets.
Daruni Boonchari
doaj  

Market insight report - Victoria's supply outlook

open access: yes, 2016
This Insights report provides a preliminary assessment of some of the potential impacts of the closure decision Hazelwood power station. Further investigation is required to gain a deeper, more holistic understanding of scenarios whereby the power system
Australian Energy Market Operator
core   +1 more source

Galois connections between sets of paths and closure operators in simple graphs

open access: yesOpen Mathematics, 2018
For every positive integer n,we introduce and discuss an isotone Galois connection between the sets of paths of lengths n in a simple graph and the closure operators on the (vertex set of the) graph.
Šlapal Josef
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

On Closure Operator

open access: yesمجلة العلوم والدراسات الإنسانية - كلية الآداب والعلوم – المرج
Closure operators have many applications inside Mathematics. In this paper we study  the closure operator  ,where  is a set , and some of its applications in algebra, topology and logic.  
NAJAH S.ABDALLA, SALMA S.ABDALLA
openaire   +1 more source

Families of language uniform theories and their generating sets

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2016
We introduce the notion of language uniform theory and study topological properties related to families of language uniform theory and their E-combinations. It is shown that the class of language uniform theories is broad enough.
S. Sudoplatov
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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