Results 71 to 80 of about 787,356 (301)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FUZZY CLOSURE SYSTEMS AND FUZZY CLOSURE OPERATORS
Summary: We introduce fuzzy closure systems and fuzzy closure operators as extensions of closure systems and closure operators. We study relationships between fuzzy closure systems and fuzzy closure spaces. In particular, two families \(F(S)\) and \(F(C)\) of fuzzy closure systems and fuzzy closure operators on \(X\) are complete lattice isomorphic.
Kim, Yong Chan, Ko, Jung Mi
openaire +2 more sources
Twenty-sixth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]
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Illinois Custom Spray Operators' School
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Numerical Range of Two Operators in Semi-Inner Product Spaces
In this paper, the numerical range for two operators (both linear and nonlinear) have been studied in semi-inner product spaces. The inclusion relations between numerical range, approximate point spectrum, compression spectrum, eigenspectrum, and ...
N. K. Sahu, C. Nahak, S. Nanda
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The Cauchy problem for the Navier-Stokes equations
In the paper we study issues of a strong solution for "essentially" loaded differential equations of the parabolic type in bounded domains. Features of the problems under consideration: for example, in the L 2( Q ) space the corresponding differential ...
A.Sh. Akysh (Akishev)
doaj
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
On boundary value problems for essentially loaded parabolic equations in bounded domains
In the paper we study issues of a strong solution for "essentially" loaded differential equations of the parabolic type in bounded domains. Features of the problems under consideration: for example, in the L 2( Q ) space the corresponding differential ...
D.M. Akhmanova +2 more
doaj
Dynamics of Resource Closure Operators [PDF]
We propose a framework for managing resources via convergent operators. Operators represent their need for a resource to a designated resource closure operator that manages the resource. We evaluate a specific design for a resource closure operator by simulation and demonstrate that the operator achieves a near-optimal balance between cost and value ...
Alva L. Couch, Marc Chiarini
openaire +2 more sources

