Results 61 to 70 of about 117,198 (266)

Closure properties of slender languages

Theoretical Computer Science, 1993
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Paŭn, Gheorghe, Salomaa, Arto
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The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The development of the Humor Structure Appreciation Scale and its relation to Sensation Seeking Inventory and Need for Closure Scale

The European Journal of Humour Research, 2018
Three related studies are presented with the aim of investigating the individual differences in humour appreciation, sensation seeking and need for closure.
Filip Sulejmanov, Ognen Spasovski, Tracey Platt   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Generative Power and Closure Properties of Watson-Crick Grammars

Applied Computational Intelligence and Soft Computing, 2016
We define WK linear grammars, as an extension of WK regular grammars with linear grammar rules, and WK context-free grammars, thus investigating their computational power and closure properties.
Nurul Liyana Mohamad Zulkufli, Sherzod Turaev, Mohd Izzuddin Mohd Tamrin, Azeddine Messikh   +3 more
doaj   +1 more source

Chain properties of rule closures [PDF]

Formal Aspects of Computing, 1990
Abstract This article introduces a generalisation of the crossed rule approach to the detection of Knuth-Bendix completion procedure divergence. It introduces closure chains, which are special rule closures constructed by means of particular substitution operations and operators, as a suitable formalism for progress in this direction ...
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A degree approach to relationship among fuzzy convex structures, fuzzy closure systems and fuzzy Alexandrov topologies

Open Mathematics, 2019
In this paper, by means of the implication operator → on a completely distributive lattice M, we define the approximate degrees of M-fuzzifying convex structures, M-fuzzifying closure systems and M-fuzzifying Alexandrov topologies to interpret the ...
Wang Lan, Wu Xiu-Yun, Xiu Zhen-Yu
doaj   +1 more source