Results 41 to 50 of about 54,524 (265)
Closure Properties and Witness Reduction
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ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Grouting Reconstruction Design of Strong Water-rich Coal Seam in Balasu Coal Mine
The 2# coal in Yuheng northern district is aquifer, which has the characteristics of high water pressure and strong water content. It brings serious safety problems to shaft construction in many coal mines in Yuheng northern district.
LIU Yang, WANG Chungang, LIANG Xiangyang, FANG Gang
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Chain properties of rule closures [PDF]
Abstract This article introduces a generalisation of the crossed rule approach to the detection of Knuth-Bendix completion procedure divergence. It introduces closure chains, which are special rule closures constructed by means of particular substitution operations and operators, as a suitable formalism for progress in this direction ...
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ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu +7 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Toy Model for Torsorial Nature of Representations
This paper presents a toy model for the representation related phenomena. It is the representation that is always referred to. The represented thing in itself is indeterminate existence at a fundamental level of understanding.
Makoto Yoshitake
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Closure properties of slender languages
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Gheorghe Paun, Arto Salomaa
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

