Results 71 to 80 of about 525,933 (279)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Categorical Structures in Rough Set Theory and Information Systems
MathematicsUsing the concept of category, we provide some insight into and prove an intrinsic property of the category AprS of approximation spaces and continuous functions.
Yu-Ru Syau, Churn-Jung Liau, En-Bing Lin
doaj +1 more source
PLoS ONE, 2019 IntroductionOnly a few, large population-based studies, have reported on whiplash-associated disorder (WAD). However, none of them have investigated the influence of crash severity on WAD outcome. In the present study, we aimed to determine whether crash
Kazuhiro Hayashi +4 more
doaj +1 more source
Evaluation of the 1-D hyperbolic quadrature method of moments for non-equilibrium flows [PDF]
ESAIM: Proceedings and SurveysWhen considering moment methods for the resolution of the free-transport term of the 1-D kinetic equation, the hyperbolic quadrature method of moments (HyQMOM) closure introduced in [12] leads to a globally hyperbolic system of conservation equations ...
Laurent Frédérique, Fox Rodney O.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Closures and generating sets related to combinations of structures
Известия Иркутского государственного университета: Серия "Математика", 2016 We investigate closure operators and describe their properties for $E$-combinations and $P$-combinations of structures and their theories including the negation of finite character and the exchange property.
S. Sudoplatov
doaj
The average and closure problem of turbulence theory resolved in random space
Journal of Hydrology and HydromechanicsThe problem above marked as resolved is more than a hundred years known as the closure problem of turbulence. Extending its name follows from below presented knowledge that to be its solution successful it is necessary to find an effective averaging tool
Kosorin Karol
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Seismic Vulnerability and Property Losses to the Portuguese Industrial Steel Building Stock
U.Porto Journal of Engineering, 2017 Industry plays a key role in the economy of a country, people welfare and socio-economic resilience to natural disasters. Earthquakes are known to have damaging impacts on industrial property and activity, oftentimes resulting in costly structural and ...
Miguel Araújo +2 more
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Chain properties of rule closures [PDF]
Formal Aspects of Computing, 1990 Abstract This article introduces a generalisation of the crossed rule approach to the detection of Knuth-Bendix completion procedure divergence. It introduces closure chains, which are special rule closures constructed by means of particular substitution operations and operators, as a suitable formalism for progress in this direction ...
openaire +2 more sources