Results 151 to 160 of about 1,411,417 (298)

Basic Properties of Closure Spaces

open access: yes, 2002
This technical report summarized facts from the basic theory of generalized closure spaces and gives detailed proofs for them. Many of the results collected here are well known for various types of spaces.
Bärbel M. R. Stadler, Peter F. Stadler
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Closure spaces

open access: yes
Hlavním cílem této bakalářské práce je systematické vybudování abstraktní teorie uzávěrových prostorů a demonstrace jejího sjednocujícího charakteru napříč matematickými disciplínami.
Frolík, Matyáš
core  

Some properties of ordered Cech closure spaces

open access: yes, 2017
Bu tez yedi bölümden oluşmaktadır. İlk bölüm giriş kısmına ayrılmıştır. İkinci bölümde; kapanış uzayı ve sıralama ile ilgili bazı temel kavramlar verilmiştir.
Eroğlu, İrem
core  

Home - About - Disclaimer - Privacy