In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Case Report: Fournier's gangrene occurring in the setting of intestinal obstruction complicated by suspected intra-abdominal infection, successfully managed with repeated surgical debridement. [PDF]
Wu T, Hu N, Ma Y.
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
New Surgical Technique for Cleft Hand and Foot Using a Lateral Pantaloon Flap. [PDF]
Umeda C +4 more
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Theoretical foundations of soft topological granular structures for multi-criteria social network analysis. [PDF]
Oza A.
europepmc +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Case Report: Acute angle-closure glaucoma as the initial presentation of autosomal recessive bestrophinopathy caused by compound heterozygous <i>BEST1</i> mutations. [PDF]
Lu R, Zhou L, Tang L, Li X, Cao G.
europepmc +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Systematic Laparoscopic Excision and Reconstruction of Bladder Endometriosis With Deep Myometrial Infiltration: A Step-by-Step Surgical Technique and Educational Case Report. [PDF]
Correa ME +3 more
europepmc +1 more source

