Results 81 to 90 of about 1,411,417 (298)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Hopf structures on closure spaces
This study extends algebraic perspectives to non-topological closure spaces by introducing Hopf structures. We define closure Hopf spaces and groups, investigate their properties, and explore homotopy theory within this framework.
Demiralp, Sibel, Ege, Özgür
core +1 more source
Quotient Structure of Interior-closure Texture Spaces
, 2015 In this paper, we consider quotient structure and quotient difunctions in the context of interior and closure operators on textures in the sense of Dikranjan-Giuli.
Dost, Senol
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Topological Structure of Vague Soft Sets
Abstract and Applied Analysis, 2014 We introduce vague soft topological spaces which are defined over an initial universe with a fixed set of parameters. The notions of vague soft open sets, vague soft closed sets, vague soft interior, vague soft closure, and vague soft boundary are ...
Chang Wang, Yaya Li
doaj +1 more source
Other title: Hospital closure recommendations
, 1995 "November 30, 1995."Includes bibliographical ...
Kansas Hospital Closure Commission.
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Applying Cech rough closure theory to binary hypercube graphs [PDF]
Mathematics and Computational SciencesThe present study examines hypercube graphs through the lens of Čech rough closure theory (ČRCT). Leveraging the binary representation and inherent symmetry of hypercubes, we introduce a closure-based approach for modelling uncertainty and vagueness in ...
Simson Jackson, Anto Sherine I
doaj +1 more source