Results 61 to 70 of about 274,994 (265)

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

CADA: A Flexible and Elastic DDoS Mitigation Architecture

open access: yesIEEE Access
The rigidity of traditional hardware DDoS mitigation frameworks is insufficient for handling complex and varied DDoS attacks. To address this, we introduce the Cloud-native Anti-DDoS Architecture (CADA), which is designed to ensure flexibility and ...
Junrui Wu   +7 more
doaj   +1 more source

AI engineering technology solutions in network intelligence

open access: yesDianxin kexue, 2022
Depending on AI technology, network intelligence is becoming an important initiative for communication industry to enhance network empowerment externally, and to achieve cost reduction and efficiency internally.The difficulties implementing network ...
Mingwei ZHU
doaj  

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Core idea、technical architecture and strategic significance of “5G+” system

open access: yesDianxin kexue, 2020
Based on the investigation of digital native evolution and case analysis,the concept framework of “5G+native” was put forward to describe the application scenarios and enterprises highly dependent on 5G high-performance network connection,its core idea ...
Kang CAI, Xiaohong LIAO, Hua TAN
doaj  

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

EbbRT: a customizable operating system for cloud applications [PDF]

open access: yes, 2015
Efficient use of hardware requires operating system components be customized to the application workload. Our general purpose operating systems are ill-suited for this task.
Appavoo, Jonathan   +4 more
core   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

open access: yesAdvanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin   +16 more
wiley   +1 more source

An industrial internet business management platform that supports the cloud-native

open access: yesDianxin kexue, 2022
Aiming at the trend of industrial enterprises facing the evolution from the traditional business management information architecture to the cloud-native platform management, an evolutionary architecture of the transitional industrial internet business ...
Wenzhe WANG   +8 more
doaj  

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