Results 181 to 190 of about 96,379 (348)

Risk of diabetes mellitus with olanzapine compared to clozapine: A systematic review and meta‐analysis

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Olanzapine and clozapine are second‐generation antipsychotics commonly associated with metabolic side effects. In Japan, olanzapine is designated as “principally contraindicated” for patients with diabetes, while clozapine is “used with caution,” despite similar pharmacological profiles.
Keigo Onda, Rizal Ichwansyah, Shuken Boku   +2 more
wiley   +1 more source

M100907 and Clozapine, but not Haloperidol or Raclopride, Prevent Phencyclidine-Induced Blockade of NMDA Responses in Pyramidal Neurons of the Rat Medial Prefrontal Cortical Slice [PDF]

, 1998
R. Wang
openalex   +1 more source

DOTS Awareness and the Myths and Misconceptions about DOTS among Medical Practitioners in Mysore [PDF]

, 2012
Background: Annually 2 million people in India develop Tuberculosis and 330,000 die. WHO-recommended DOTS strategy was pilot-tested in 1993 and launched as Revised National Tuberculosis Control Program (RNTCP) in 1997. Awareness of DOTS among the doctors
Khan, MA, Nagaraja, V, Sankapithilu, GB
core   +1 more source

Factors associated with treatment failure after discharge in inpatients with schizophrenia spectrum disorders: A retrospective observational study

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Schizophrenia spectrum disorders are among the most serious mental illnesses that cause social dysfunction. Patients with schizophrenia spectrum disorders are prone to recurrence, and those who require hospitalization are at a high risk; hence, preventing treatment failure after discharge is essential.
Yoshitaka Saito, Hiroyuki Muraoka, Takayuki Yokoyama, Katsuichiro Shimizu, Yukihiro Tanno, Nagomi Kida, Taiyo Nishikawa, Shin Miyake, Yukio Kenmotsu, Kosei Kamimura, Hirohito Kato, Yuka Noguchi, Seita Tsuchida, Ryutaro Suzuki, Yuki Yoshimura, Shoko Miura, Shunsuke Kamitani, Takaaki Hirooka, Enami Sawayama, Satoru Oishi, Ken Inada   +20 more
wiley   +1 more source

A psychiatric medication, clozapine, induces autophagy and apoptosis in breast cancer cells through reactive oxygen species.

PLoS ONE
Cancer patients with psychotic disorders have occasionally exhibited reduced tumor sizes following long-term antipsychotic treatment. Previous studies have shown that antipsychotic drugs, such as clozapine, could inhibit cancer cell proliferation, but ...
Ya-Chun Fan, Shih-Chao Lin, Po-Jung Lai, Pei-Chun Lai, Germain Maurus, Shiow-Yi Chen   +5 more
doaj   +1 more source

Clozapine: Selective Labeling of Sites Resembling 5HT6 Serotonin Receptors May Reflect Psychoactive Profile [PDF]

, 1995
Charles E. Glatt, Adele M. Snowman, David R. Sibley, Solomon H. Snyder   +3 more
openalex   +1 more source

Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis

British Journal of Psychiatry, 2016
D. Siskind, Lara McCartney, R. Goldschlager, S. Kisely   +3 more
semanticscholar   +1 more source

The fast‐dissociating D2 antagonist antipsychotic JNJ‐37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment

British Journal of Pharmacology, Volume 182, Issue 22, Page 5574-5595, November 2025.
Abstract Background and Purpose Pharmacological activation of neuronal M‐current mediated by Kv7 (Kv7.2–5) potassium channels is a validated mechanism for epilepsy treatment. However, since the market withdrawal of the prototype Kv7 activator retigabine, no Kv7 activator is clinically available for this condition.
Lidia Carotenuto, Oliver Keminer, Giusy Carleo, Andrea Zaliani, Antonio Leo, Rita Citraro, Giovambattista De Sarro, Nina Dirkx, Marcus Kaji, Sarah Weckhuysen, Jeanette Reinshagen, Vincenzo Barrese, Natascia Guida, Carmine Ostacolo, Francesco Miceli, Philip Gribbon, Maurizio Taglialatela   +16 more
wiley   +1 more source

Predictors of clozapine concentration and psychiatric symptoms in patients with schizophrenia.

PLoS ONE
Clozapine has superior efficacy to other antipsychotics, especially in patients with treatment-resistant schizophrenia. However, its pharmacokinetics and pharmacodynamics vary largely among patients.
Sang-In Park, Seoyoung Kim, Kwanwoo Park, Uijeong Yu, Yunjeong Jang, Bo-Hyung Kim, Ji Hyun Lee, Euitae Kim   +7 more
doaj   +1 more source

Clozapine and lorazepam administration in pregnancy [PDF]

, 1996
Vittorio Di Michele, Luca A. Ramenghi, Giuseppe Sabatino   +2 more
openalex   +1 more source