Results 161 to 170 of about 39,176 (275)

Combined Inhibition of TRPM4/NMDA Receptor Complex and Extrasynaptic NMDA Receptors Is Candidate Therapeutic Target for Suppression of Epileptic Seizures and Improvement of Cognitive Impairments

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Cognitive impairments are important therapeutic targets in epilepsy medication; however, effective pharmacological treatments for epilepsy patients with comorbid cognitive impairment have not been established. Effects of chronic administration of MK‐801 (noncompetitive NMDA receptor inhibitor), memantine (low‐affinity extrasynaptic‐NMDA ...
Motohiro Okada   +3 more
wiley   +1 more source

The comparison of clozapine and haloperidol effects on plasma thiol groups in healthy subjects

open access: yes, 2012
Differentiated effects of antipsychotics: haloperidol and clozapine on oxidative stress biomarkers were analysed. It has not been determined yet in what way clozapine and haloperidol affect human plasma thiol groups (-SH).
Anna Dietrich-Muszalska   +5 more
core  

Restoring Septohippocampal Cholinergic Signaling Rescues Surgery‐Induced Neurogenesis and Memory Deficits in Aged Mice

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Surgery‐induced MS/vDB → DG cholinergic decline impairs hippocampal neurogenesis and memory in aged mice; galantamine‐mediated cholinergic potentiation or sustained chemogenetic activation rescues these deficits, highlighting therapeutic potential for POCD.
Lei Lei   +8 more
wiley   +1 more source

Involuntary Clozapine Treatment: A Systematic Review

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 6, Page 595-609, June 2026.
ABSTRACT Introduction We aimed to synthesize the information relevant for clinical practice on involuntary clozapine treatment. Methods Articles were identified with MEDLINE, Web of Sciences and PsycINFO search from inception through September 2025 (PROSPERO database registration CRD420251234475).
Hélène Verdoux   +2 more
wiley   +1 more source

A scoping review of genetic studies of treatment-resistant schizophrenia. [PDF]

open access: yesFront Genet
Das U   +7 more
europepmc   +1 more source

Clozapine is underutilized.

open access: yesShanghai archives of psychiatry, 2012
openaire   +2 more sources

Rare and very rare adverse effects of clozapine

open access: yes, 2015
Pasquale De Fazio,1 Raffaele Gaetano,1 Mariarita Caroleo,1 Gregorio Cerminara,1 Francesca Maida,2 Antonio Bruno,3 Maria Rosaria Muscatello,3 Maria Jose Jaén Moreno,4 Emilio Russo,2 Cristina Segura-García1 1Department of Health Sciences ...
Russo E   +9 more
core  

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