Results 151 to 160 of about 39,176 (275)

Association Between Psychiatrists' Subjective Clinical Behavior Scores and Objective Quality Indicators Based on Discharge Prescriptions: A Nationwide Multicenter Study Based on the EGUIDE Project

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Association between quality indicators and clinical behaviors related to the guidelines for schizophrenia. ABSTRACT Aim Psychiatrists often perceive their clinical practices as guideline‐concordant; however, discrepancies frequently exist between perceived and actual prescribing behaviors.
Kazuhiko Yamamuro, Naomi Hasegawa, Yusuke Arai, Hikaru Hori, Hiroyuki Muraoka, Toru Horinouchi, Naoki Hashimoto, Shinichiro Ochi, Takashi Tsuboi, Hirotaka Yamagata, Junya Matsumoto, Satsuki Ito, Toshiaki Onitsuka, Kazutaka Ohi, Hisashi Yamada, Jun‐ichi Iga, Ken Inada, Koichiro Watanabe, Norio Yasui‐Furukori, Ryota Hashimoto   +19 more
wiley   +1 more source

Echocardiography and clozapine: Is current clinical practice inhibiting use of a potentially life-transforming therapy?

, 2017
Approximately 33% of patients with schizophrenia are treatment-refractory, yet clozapine remains underused, even though it is the most effective treatment.1,2 One barrier is routine echocardiography, which in Australia is performed before clozapine ...
Kisely, Steve, Robinson, Gail, Flanagan, Robert J, Wheeler, Amanda J, Siskind, Dan   +4 more
core  

Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross‐Sectional Study

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
In chronic schizophrenia, serum adiponectin levels were positively associated with antipsychotic dosage, particularly with multi‐acting receptor‐targeted antipsychotics and were influenced by gender and hospitalization period. These findings highlight gender‐specific metabolic regulation and the importance of monitoring adipokines during long‐term ...
Yasuhiro Ohno, Kiyomi Saito, Keita Hanabusa, Ayaka Nakai, Tomoko Nagai, Noriko Hida, Kenji Sanada   +6 more
wiley   +1 more source

Antipsychotic treatment in schizophrenia: balancing relapse prevention and functional recovery

Schizophrenia
Jan P. A. M. Bogers
doaj   +1 more source

Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
This graphical summary illustrates the efficacy and safety of brexpiprazole (2–4 mg) in patients with schizophrenia. The meta‐analysis demonstrates significant improvement in clinical outcomes, with reductions in Positive and Negative Syndrome Scale (PANSS) and Clinical Global Impression ‐ Severity scale (CGI‐S) scores, indicating better symptom ...
Sher Bano, Aashan Ahmad, Abdul Haseeb Mohammed, Ismailova Rushana Nurbekovna, Saja Saad, Noor Fatima, Muhammad Bilal Akbar, Zainab Salahuddin, Sadikun Nabi, Mohammad Mustafa Ababneh, Laiba Ajmal, Sidra Hariss, Hiba Manaf, Farah Saleh, Raouf Khan   +14 more
wiley   +1 more source

Environmental and behavioral controls of the expression of clozapine tolerance: Evidence from a novel across-model transfer paradigm

, 2013
Repeated administration of antipsychotic drugs induces a sensitization-like or tolerance-like effect in many behavioral tasks, including the conditioned avoidance response (CAR) and the phencyclidine (PCP)-induced hyperlocomotion, two rodent models with ...
Li, M (reprint author), Univ Nebraska, Dept Psychol, 238 Burnett Hall, Lincoln, NE 68588 USA., Li, Ming, Sui, Nan, Feng, Min   +3 more
core  

Clinical dilemma of mood stabilizer augmentation in treatment‐resistant schizophrenia with residual phase: A case report of valproate‐associated hypoglycemia and cytopenia, and subsequent lithium response

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Mood stabilizer augmentation is frequently used in treatment‐resistant schizophrenia despite limited guideline recommendations. Evidence for its efficacy and safety in the residual phase, however, remains insufficient. Case Presentation A 49‐year‐old Japanese woman with treatment‐resistant residual schizophrenia exhibited persistent
Yoshiki Kasagi, Naomichi Okamoto, Reiji Yoshimura   +2 more
wiley   +1 more source

Clozapine prescribing in Germany: temporal trends and regional variations, 2012-2022. [PDF]

Schizophrenia (Heidelb)
Scholle OHF, Riedel O, Qubad M, Dörks M, Kollhorst B, Bittner RA, Bachmann CJ.   +6 more
europepmc   +1 more source

Acceptability of Atropine Eyedrops Administered Sublingually for Sialorrhea Treatment Related to Neurological Conditions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Off‐label use of anticholinergic agents (atropine eye drops) administered sublingually are a first‐line treatment in standard clinical practice in France to treat sialorrhea in patients with neurological conditions. The ability and willingness to using and administering such medication have become key factors to ensure safe and effective ...
Hugues Michelon, Clémence Lefèvre‐Dognin, Julie Paquereau, Raphaëlle Guidoni, Vincent Boudy, Fabrice Ruiz, Thibault Vallet   +6 more
wiley   +1 more source

Severe neutropenia unrelated to clozapine in patients receiving clozapine

Background: Clozapine is known to cause agranulocytosis. Mandatory monitoring schemes are aimed at reducing the risk of agranulocytosis and of the consequences of agranulocytosis.
Vallianatou, Kalliopi, Gandhi, Shreyans, Casetta, Cecilia, MacCabe, James; id_orcid, Howes, Oliver, Taylor, David; id_orcid   +5 more
core   +1 more source