Results 131 to 140 of about 39,176 (275)

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 178-192, July 2026.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source

Clozapine reinitiation following a "red result" secondary to chemotherapy

, 2013
Tariq Munshi, Mir Mazhar, Tariq HassanDepartment of Psychiatry, Kingston General Hospital, Kingston, ON, CanadaAbstract: We describe a case of a patient whose clozapine was discontinued after a "red result" following R-CHOP (rituximab with ...
Hassan T, Munshi T, Mazhar M
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Dissociation Between Hemodynamic and Metabolic Responses to Chemogenetic Modulation of Astrocytes in Mouse Visual Cortex

Glia, Volume 74, Issue 7, July 2026.
Chemogenetic astrocytic modulation in mouse visual cortex showed no local glucose uptake change (PET) but enhanced hyperemia and vasomotion (fUSi), revealing a local dissociation with a negative correlation between metabolic and hemodynamic signals.
Mickaël Pereira, Benjamin Vidal, Marco Valdebenito, Fatima Cheataini, Caroline Bouillot, Louis Vidal, Liam Nestor, Dimitri De Bundel, Ilse Smolders, Marine Droguerre, Luc Zimmer   +10 more
wiley   +1 more source

Metabolic monitoring and management among clozapine users

, 2016
Objective: To assess, among clozapine users, the rates of monitoring, presence and treatment of metabolic syndrome and its components. Methods: A chart review was conducted of all clozapine users who were followed up in community mental health clinics at
Tso, Grace, Jayasooriya, Thilini, Kisely, Steve, Siskind, Dan, Kumar, Puja   +4 more
core   +1 more source

Effectiveness of a Psychiatrist‐Led Clinic for Metabolic Health in Severe Mental Illness: A Retrospective Chart Review Study

Acta Psychiatrica Scandinavica, Volume 154, Issue 1, Page 74-88, July 2026.
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios, Femin Prasad, Riddhita De, Kateryna Maksyutynska, Akash PrasannaKumar, Vittal Korann, Tariq Ahmed, Marcos Sanches, Leah Burton, Mohammed A. Alarabi, Tanner Isinger, Michelle Desanti, Rebecca Oliveira, Daphne J. Korczak, Ariel Graff‐Guerrero, Gary Remington, Margaret K. Hahn, Sri Mahavir Agarwal   +17 more
wiley   +1 more source

Chemogenetic Stimulation of the Dorsal Motor Nucleus of the Vagus Mitigates Autonomic Dysfunction and Memory Decline in Rat Model of Alzheimer‐Like Disease

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim To test the hypothesis that Alzheimer‐like metabolic neurodegeneration rat model leads to an autonomic dysfunction, memory impairment, and hippocampal amyloid pathology and that long‐term chemogenetic stimulation of the dorsal motor nucleus of the vagus reverses these alterations. Methods Male and female transgenic Long Evans rats received
Beatriz Pacheco Sousa, Karoline Martins dos Santos, Vagner Roberto Antunes   +2 more
wiley   +1 more source

Case series and Literature review – Clozapine Induced Transient Myocarditis. Clinical characteristics and outcomes

European Psychiatry
Introduction Clozapine is a second-generation atypical antipsychotic medication used in patients with treatment-refractory schizophrenia. Its use is limited due to its associated adverse effects, including myocarditis.
U. L. Anyeji, P. Bidkhanian
doaj   +1 more source

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared, Fatemeh Shahabi, Asieh Sadat Fattahi, Marzieh Rahimi, Mahsa Akbari Oryani, Azadeh Jabbari Nooghabi   +5 more
wiley   +1 more source

A psychiatric medication, clozapine, induces autophagy and apoptosis in breast cancer cells through reactive oxygen species.

PLoS ONE
Cancer patients with psychotic disorders have occasionally exhibited reduced tumor sizes following long-term antipsychotic treatment. Previous studies have shown that antipsychotic drugs, such as clozapine, could inhibit cancer cell proliferation, but ...
Ya-Chun Fan, Shih-Chao Lin, Po-Jung Lai, Pei-Chun Lai, Germain Maurus, Shiow-Yi Chen   +5 more
doaj   +1 more source

Influence of dose, gender, and cigarette smoking on clozapine plasma concentrations

, 2018
Michaela Mayerova,1–3 Libor Ustohal,1–3 Jiri Jarkovsky,4 Jan Pivnicka,1,5 Tomas Kasparek,1,2 Eva Ceskova1,3 1Faculty of Medicine, Masaryk University, Brno, Czech Republic; 2Department of Psychiatry, University Hospital Brno, Brno, Czech ...
Mayerova M, Kasparek T, Ustohal L, Ceskova E, Pivnicka J, Jarkovsky J   +5 more
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