Results 111 to 120 of about 69,470 (266)

Using the CLSI rAST breakpoints of Enterobacterales in positive blood cultures

Diagnostic Microbiology and Infectious Disease
The objective of this study was to provide the clinic with rapid and accurate results of antimicrobial susceptibility testing for the treatment of patients with bloodstream infections. To achieve this, we applied the Clinical and Laboratory Standards Institute (CLSI) blood culture direct rapid antimicrobial susceptibility test (rAST) to assess the ...
Jin Deng, YunHe An, Mei Kang
openaire   +2 more sources

MIC breakpoints for Pseudomonas aeruginosa according to EUCAST and CLSI guidelines.

, 2015
Abbreviations: CLSI: Clinical and Laboratory Standards Institute; EUCAST: European Committee on Antimicrobial Susceptibility Testing; MIC: minimum inhibitory concentration.
Josef Yayan (659913), Beniam Ghebremedhin (625821), Kurt Rasche (799310)   +2 more
core   +1 more source

Seasonal and Regional Variation of the Chemical Composition and Antimicrobial Activity of Essential Oils From Piper marginatum Jacq.

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Evaluating Piper marginatum essential oils across three Brazilian biomes reveals significant chemical and antimicrobial variations driven by seasonal and regional factors. Sixty compounds are identified, including a novel (Z)‐phenylpropanoid reported for the first time. Multivariate analysis correlates environmental stressors with specialized metabolic
Rebeca Gabriel de Camargo, Marta Cristina Teixeira Duarte, Diones Krinski, Ana Paula Palaro Klein Hendges, Aurea Portes Ferriani, Francisco de Assis Marques, Thalita Gilda Santos, Beatriz Helena Lameiro de Noronha Sales Maia   +7 more
wiley   +1 more source

Essential agreement (EA) and categorical agreement (CA) between ATB FUNGUS 3 (visual and automated readings) and CLSI BMD.

, 2014
aFor these species/drugs, the CAs (%) were calculated based on breakpoints described in CLSI M27-S4; others were calculated based on ECVs.bFor species/drugs analyzed by ECVs, minor error was unavailable because there was no “SDD”.Essential agreement (EA)
He Wang (250350), Timothy Kudinha (647162), Lei-Li Mao (668225), Ying-Chun Xu (647163), Hao-Ran Zhao (668226), Li Zhang (8200), Fanrong Kong (218191), Meng Xiao (591353)   +7 more
core   +1 more source

Nicotinamide and Sodium Butyrate Double the Pool of Treatment‐Exclusive Metabolites in the Endophytic Fungus Curvularia sp. G6‐32

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Epigenetic modulators nicotinamide and sodium butyrate reshape the chemical landscape of the endophytic fungus Curvularia sp. G6‐32. Combining the OSMAC strategy with UHPLC‐MS/MS metabolomics and molecular networking reveals a more than twofold rise in treatment‐exclusive metabolites, including diketopiperazines and potentially bioactive natural ...
Guilherme Edison Almeida Pega, Laís Stella Perassolli Nicchio, Andressa Domingos Polli, Francielli Alana Pereira Valeze, Évelin Lemos de Oliveira, Eduardo Cesar Meurer, Débora Cristina Baldoqui, João Lúcio Azevedo, Julio Cesar Polonio   +8 more
wiley   +1 more source

Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access

Transplant Infectious Disease, EarlyView.
Jian Mei Li, Jacqueline E. Clark, Tiffany Wu   +2 more
wiley   +1 more source

Clinopodium nepeta Essential Oil and Its Major Constituents Pulegone and Menthone: Composition and Activity Against Verticillium dahliae, Phytophthora infestans, and Macrophomina phaseolina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Chemical fractionation of Clinopodium nepeta essential oil reveals pulegone and menthone as markedly more potent antifungal isolates than the whole oil, with activity varying among pathogens. Pulegone exhibits superior efficacy against Verticillium dahliae and Phytophthora infestans, whereas menthone shows enhanced activity against Macrophomina ...
Mohamed Taibi, Amine Elbouzidi, Mounir Haddou, Abdessamad Beraich, Abdellah Baraich, Reda Bellaouchi, Mohamed Addi, Khalid Chaabane, Bassem Jaouadi, Nadia Zarai, Bouchra El Guerrouj, Abdeslam Asehraou   +11 more
wiley   +1 more source

In Reply to Flawed Critique of CLSI Guideline EP05-A2

The Journal of Applied Laboratory Medicine, 2022
Robert Frenkel, Ian Farrance
openaire   +2 more sources

Mannosylxylarinols A and B, Two New 3,4‐Seco‐ergostane‐type Steroidal Saponins From the Fungus Xylaria necrophora SZSS1‐2‐2

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Two new 3,4‐seco‐ergostane saponins (1–2) and four known compounds were isolated from Xylaria necrophora. Structures were elucidated via spectroscopy, ECD, and computational NMR. Compound 5 selectively inhibited BV2 microglial cells (IC50 = 17.10 µM), while all compounds showed no antimicrobial activity against tested microorganisms. ABSTRACT Two new 3,
Qian Luo, Yu Yang, Rui Xu, Xue Zhao, Hui‐Fang Tan, Yu‐Ying Wei, Er‐Wei Li, Li‐Xia Chen, You‐Zhi Zhang, Chang‐Wei Li   +9 more
wiley   +1 more source

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 914-929, October 2026.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg, José M.A. Moreira   +1 more
wiley   +1 more source