Results 101 to 110 of about 805,391 (299)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Competition in Soccer Leagues [PDF]
In the present paper a model of competition between sports clubs in a sports league is presented. Clubs are endowed with initial players but at a cost clubs are able to sell their initial players and buy new players.
Bodil Olai Hansen, Mich Tvede
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Women's clubs: Dispersing Shakespeare across America [PDF]
, 2011 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Symbiosis - A Transatlantic Journal.This article explains the importance of women's clubs in America and their role in the ...
Leahy, W, Whetstone, T
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Convergence and Divergence among Technology Clubs [PDF]
The paper investigates cross-country differences in technology in a large sample of developed and developing economies over the 1990s. The empirical analysis indicates the existence of three technology clubs with markedly different levels of ...
Fulvio Castellaci
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Europeanisation, Bosman and the Financial ‘Crisis’ in English Professional Football: Some Sociological Comments [PDF]
, 2007 [From the introduction]. During the last two decades there has been growing concern over what has been described as the financial ‘crisis’ in English football. This is not just a media-inspired view, but one that has emanated increasingly from within the
Platts, Chris,, Smith, Andy.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Freedom of entry, market size and competitive outcome: evidence from English soccer [PDF]
The paper tests, in the context of an open sports league, whether greater success is achieved by clubs in markets with larger populations. The relationship is strong but, to a limited extent, mitigated by more clubs establishing in large markets.
B Buraimo, D Forrest, R Simmons
core +1 more source
The 2010 regulations on golf groove design: impact on ball flight characteristics during a controlled shot. [PDF]
, 2013 The purpose of this study was to investigate the difference in the amount of spin that can be generated during a controlled golf shot, as a result of the 2010 rule change regarding restrictions applied to the design of the grooves on the clubface ...
Burnham, Paul +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source