Results 91 to 100 of about 805,391 (299)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
ADVANCES IN THE THEORY OF LARGE COOPERATIVE GAMES AND APPLICATIONS TO CLUB THEORY : THE SIDE PAYMENTS CASE [PDF]
In a series of papers (Kovalenkov and Wooders 2001a, Games and Economic Behavior, 2001b,Mathematics of Operations Research, and 1997, Journal of Economic Theory to appear), the authors have developed the framework of parameterized collections of games ...
Kovalenkov, Alexander, Wooders, Myrna
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Ambivalent Identity of Eighteenth-Century London Clubs as a Prelude to Victorian Clublife
Cahiers Victoriens et Edouardiens, 2015 From the late seventeenth century to Victorian times, gentlemen’s clubs have always oscillated between norm and dissidence. The ambivalent identity of London clubs can be highlighted through some of their main paradoxes and inherent tensions such as ...
Valérie Capdeville
doaj +1 more source
Economic Inquiry, 2004 This article proposes a theory of group formation based on the motive to seek informed opinion. Because an individual evaluates whether others are informed or not using his own priors, he identifies people with similar beliefs to be more informed than those with different beliefs.
openaire +3 more sources
How does Clubs' Organizational Design Affect Competition Among Clubs? [PDF]
We analyze competition among clubs in which the status of club members is the crucial added value accruing to fellow club members through social interaction within the club (e.g. in country clubs, academic faculties, or internet communities).
Prüfer, J., Walz, U.
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Progressive Revenue Sharing in MLB: The Effect on Player Transfers [PDF]
The 1997 collective bargaining agreement between the Major League Baseball owners and players’ union altered MLB’s system of sharing revenue sharing between clubs.
Joel G. Maxcy
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Regional inequalities and convergence clubs in the European Union new member-states [PDF]
The paper assesses on empirical grounds the level and the evolution of regional inequalities in each European Union new member-state (EU NMS) and examines the possibility for the emergence of regional convergence clubs.
Dimitris KALLIORAS +2 more
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