Results 71 to 80 of about 805,391 (299)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Yorkshire Antiquarian Club 1849–c.1860
Bulletin of the History of Archaeology, 2010 The Yorkshire Antiquarian Club was formed in York in 1849. Between that date and 1855 club members undertook a series of excavations on Bronze Age and Iron Age funerary monuments in various parts of the East and North Ridings of ...
Stephen Harrison
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Вестник Кемеровского государственного университета, 2013 The paper discusses whether the housing stock and the establishments of the welfare sphere which existed in the Kemerovo region in 1943 – 1948 satisfied the requirements of the population.
I. V. Ilyin
doaj
Corporate Social Responsibility in European Sport Clubs: Analysis and Classification of Activities/Programs [PDF]
, 2011 Aim of paper and research questions: This study seeks to understand Corporate Social Responsibility (CSR) in European sport clubs by analysing and classifying the CSR activities and programs.
Brown, A +3 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Слобожанський науково-спортивний вісник, 2019 Purpose: to prove the expediency of using training combinations to increase the level of knowledge of young athletes with basic skills in exercises with clubs.
Alla Mullagіldіna, Inna Krasova
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Science Education InternationalThis study explored the impact of the alternative learning activity (ALA) program offered in the Philippine Science High School-Ilocos Region Campus toward students’ leadership abilities.
Dominic Patric Galdonez
doaj +1 more source