Results 51 to 60 of about 321,235 (338)

Labour-Capital Relations in Professional Football: A Qualitative Research on the Phenomenon of Wage, Social Security and Labour Union in Lower Leagues [PDF]

open access: yesSportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2016
While football appeals as a charming theatrical recreation activity to the masses, at the same time it is a field of where labour capital relations emerge for those who perform it.
Muazzez Şaşmaz Ataçocuğu   +1 more
doaj  

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Clubbing with ecstasy [PDF]

open access: yesTemperature, 2014
In this issue, Parrot and Young present the results of temperature measurements in young individuals "partying" with 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy). This editorial commentary briefly summarizes the main findings of their study, provides background gained from previous animal experiments, and reviews the implications for the ...
Eugene A. Kiyatkin, Suelynn Ren
openaire   +3 more sources

Can't play, won't play: longitudinal changes in perceived barriers to participation in sports clubs across the child–adolescent transition

open access: yesBMJ Open Sport & Exercise Medicine, 2016
Background Participation in sports is associated with numerous physical and psychosocial health benefits, however, participation declines with age, and knowledge of perceived barriers to participation in children is lacking.
L. Basterfield   +7 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Identifying Economic Growth Convergence Clubs and Their Influencing Factors in China

open access: yesSustainability, 2018
Balanced and coordinated economic development across regions is a critical goal of regional economic development and new-type urbanization in China. However, few studies have examined economic growth convergence clubs at the county level.
Feng Li   +4 more
semanticscholar   +1 more source

Business Model and Institutional Evolution of European Football [PDF]

open access: yesRevista Intercontinental de Gestão Desportiva, 2020
The great challenge of this work is to debate the financial and sports transformations that have occurred in the last few years in football and have provided its modernization and economic development.
Rodrigo Mendes Ribeiro Marioni   +1 more
doaj  

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Produire des espaces sportifs décalés pour gérer un risque social: l’exemple du sport LGBT

open access: yesGeography Notebooks, 2019
The growing number of LGBT sports clubs and tournaments questions gender and sexuality related boundaries in cities. The specific spatial patterns, at various scales, create specific sporting sites and structures: temporarily isolated territories, and ...
Antoine Le Blanc
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

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