Results 91 to 100 of about 31,615 (293)

Constraining reionization using 21 cm observations in combination with CMB and Lyman-alpha forest data

, 2009
In this paper, we explore the constraints on the reionization history that are provided by current observations of the Lyman-alpha forest and the CMB.
Abraham Loeb, Barkana, Barkana, Barkana, Becker, Becker, Bolton, Bolton, Bolton, Bolton, Bouwens, Bowman, Bowman, Bromm, Bromm, Cen, Chen, Choudhury, Choudhury, Colombo, Dunkley, Fan, Faucher-Giguère, Faucher-Giguère, Faucher-Giguère, Furlanetto, Furlanetto, Furlanetto, Furlanetto, Furlanetto, Gunn, Holder, Hopkins, Hui, J. Stuart B. Wyithe, Jonathan R. Pritchard, Kaplinghat, Komatsu, Leitherer, Lidz, MacKay, Malhotra, McDonald, McQuinn, McQuinn, McQuinn, McQuinn, Meiksin, Miralda-Escudé, Miralda-Escudé, Misawa, Parsons, Pawlik, Press, Pritchard, Pritchard, Ricotti, Ricotti, Santos, Schaye, Schaye, Schaye, Scheuer, Shaver, Songaila, Stark, Storrie-Lombardi, Tanvir, Tegmark, Trac, Trac, Weinberg, Zahn, Zaldarriaga   +73 more
core   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Mass-loss rates of Very Massive Stars

, 2014
We discuss the basic physics of hot-star winds and we provide mass-loss rates for (very) massive stars. Whilst the emphasis is on theoretical concepts and line-force modelling, we also discuss the current state of observations and empirical modelling ...
A. D. Code, A. E. Wright, A. I. MacFadyen, A. J. Marle van, A. W. A. Pauldrach, A. W. A. Pauldrach, A. W. Fullerton, A.W.A. Pauldrach, B. Davies, B. Davies, B. Surlan, C. A. Iglesias, C. Leitherer, C. Trundle, C. V. Rodrigues, D. C. Abbott, D. C. Abbott, D. H. Cohen, D. J. Hillier, D. J. Hillier, D. Schaerer, E. A. Milne, E. Anders, F. Martins, G. Gräfener, G. Gräfener, G. Gräfener, G. Meynet, G. Meynet, H. Belkus, I. Baraffe, I. Brott, J. Castor, J. H. Groh, J. H. Groh, J. J. Eldridge, J. Krticka, J. O. Sundqvist, J. Puls, J. Puls, J. Puls, J. Puls, J. Puls, J. S. Vink, J. S. Vink, J. S. Vink, J. S. Vink, J.-P. Zahn, K. G. Gayley, K. G. Gayley, L. B. Lucy, L. B. Lucy, L. B. Lucy, L. M. Oskinova, L. Muijres, L. Muijres, L. Muijres, L. R. Yungelson, M. Cantiello, M. Limongi, M. R. Mokiem, N. J. Shaviv, N. Langer, N. Panagia, N. Smith, N. Smith, N. Smith, N. Yusof, P. E. Müller, P. E. Müller, P. S. Conti, Q.-K. Li, R. H. D. Townsend, R. Kotak, R. M. Humphreys, R.-P. Kudritzki, S. P. Owocki, S. P. Owocki, S. P. Owocki, S.-C. Bouret, T. J. Harries, T. Repolust, U. Springmann, W. Glatzel, W.-R. Hamann, W.-R. Hamann   +85 more
core   +1 more source

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science, EarlyView.
ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
wiley   +1 more source

X-ray exploration of the outskirts of the nearby Centaurus cluster using Suzaku and Chandra

, 2013
We present Suzaku observations of the Centaurus cluster out to 0.95r200, taken along a strip to the north west. We have also used congruent Chandra observations of the outskirts to resolve point sources down to a threshold flux around 7 times lower than ...
Fabian, A. C., Sanders, J. S., Simionescu, A., Tawara, Y., Walker, S. A.   +4 more
core   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Quantifying properties of ICM inhomogeneities

, 2012
We present a new method to identify and characterize the structure of the intracluster medium (ICM) in simulated galaxy clusters. The method uses the median of gas properties, such as density and pressure, which we show to be very robust to the presence ...
Churazov, E., Kravtsov, A., Lau, E. T., Nagai, D., Sunyaev, R., Zhuravleva, I.   +5 more
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Photographic assessment of overstory and understory leaf area index in beech forests under different management regimes in Central Italy

Metsanduslikud Uurimused, 2014
Forest understory may be strongly affected by silvicultural practices such as thinning, which simultaneously modulates the overstory canopy cover and influences the availability of light.
Chianucci Francesco, Puletti Nicola, Venturi Ernesto, Cutini Andrea, Chiavetta Ugo   +4 more
doaj   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source