Results 161 to 170 of about 31,615 (293)

Genetic associations with education have increased and are patterned by socioeconomic context: Evidence from 3 studies born 1946-1970. [PDF]

Proc Natl Acad Sci U S A
Morris TT, Wright L, Shireby G, Bann D.
europepmc   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

Cardiac function and extracellular matrix morphology are altered by chronic high fat diet in Drosophila larvae. [PDF]

PLoS One
Andrews RM, Naik S, Pelletier K, Jacobs JR.   +3 more
europepmc   +1 more source

Unpacking early risks for peer victimization: A network analysis of early temperament and polygenic risk scores

JCPP Advances, EarlyView.
Abstract Background Children who show difficult temperament are at risk of peer victimisation, which in turn associates with numerous negative outcomes later in life. We used network analysis to examine whether specific aspects of difficult temperament contributed to these associations, and whether the links were moderated by variations in genetic ...
Tom C.‐H. Wu, Deniz Konac, Liliana Garcia‐Mondragon, Alex F. Martin, Barbara Maughan, Ted Barker   +5 more
wiley   +1 more source

Differential performance of polygenic risk scores for heart disease in Hispanic/Latino subgroups: Findings of the Hispanic Community Health Study/Study of Latinos. [PDF]

HGG Adv
Hutten CG, Boehm FJ, Smith JA, Spitzer BW, Wassertheil-Smoller S, Isasi CR, Cai J, Unkart JT, Sun J, Persky V, Daviglus ML, Sofer T, Argos M.   +12 more
europepmc   +1 more source

Evaluation of Panoramic Acquisition Errors by Predoctoral Dental Students

Journal of Dental Education, EarlyView.
Abstract Objectives Panoramic radiography is commonly used in the management of dental‐alveolar pathology. Novice clinicians are prone to technical errors that diminish the diagnostic quality of radiographs. The objective of this study was to analyze technical errors made during panoramic exposures by third‐year (D3) dental students in order to enhance
Zachary B. Featherstone, Xiaoxi Cui, Wenjian Zhang   +2 more
wiley   +1 more source

Studying rare variant polygenic risk scores using whole exome sequencing and imputed genotype data. [PDF]

Commun Biol
Kang JO, Kwon SY, Jung HU, Jung H, Lim JE, Oh B.   +5 more
europepmc   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

Polygenic risk for Alzheimer's disease in healthy aging: age-related and APOE-driven effects on brain structures and cognition. [PDF]

Genome Med
Chen HJ, Dong X, Wang Y, Wang K, Feng G, Bai T, Zhang M, Gan K, Peng JJ, Huang W, Zhang Z, Shu N, Ma G.   +12 more
europepmc   +1 more source

Multicenter Validation Study of the Clinical Diagnostic Criteria for IgG4‐Related Sclerosing Cholangitis 2020 in Japan

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background The diagnostic performance of clinical diagnostic criteria for IgG4‐related sclerosing cholangitis 2020 (IgG4‐SC2020) has not been fully validated since its proposal as a revision of the 2012 criteria (IgG4‐SC2012). Methods We conducted a multicenter validation study to evaluate the diagnostic performance of IgG4‐SC2020 using ...
Itaru Naitoh, Takahiro Nakazawa, Kensuke Kubota, Takayoshi Nishino, Akira Nakamura, Dai Inoue, Takanori Sano, Kazuhiro Kikuta, Yusuke Kurita, Kazuro Chiba, Tsukasa Ikeura, Hiroyuki Matsubayashi, Takuya Ishikawa, Masaki Kuwatani, Terumi Kamisawa, Ichiro Yasuda, Mitsuhiro Kawano, Atsushi Masamune, Japan Pancreatitis Study Group, Yoko Abe, Atsushi Irisawa, Hiroyuki Tanaka, Eizaburo Ohno, Tatsuru Maruo, Toshiharu Ueki, Rei Suzuki, Tadayuki Takagi, Hiromasa Ohira, Shirou Tanoue, Akio Ido, Takahiro Komori, Kayashima Atsuo, Masayasu Horibe, Eisuke Iwasaki, Masahiro Tsujimae, Yuzo Kodama, Kazushige Uchida, Masayuki Ueno, Kenji Notohara, Shotaro Kakehashi, Nao Fujimori, Eiji Nakatani, Yasuki Hori, Michihiro Yoshida, Hiroki Kawashima, Kazunao Hayashi, Shuji Terai, Kosaku Morimoto, Ryosuke Sato, Kazuyuki Matsumoto, Hironari Kato, Yoshiharu Masaki, Hiroshi Nakase, Toshihiko Arizumi, Atsushi Tanaka, Ryotaro Matusmoto, Tetsuya Takikawa, Ryosuke Tonozuka, Takao Itoi, Kenji Hirano, Nobuhiko Hayashi   +60 more
wiley   +1 more source