Results 41 to 50 of about 10,963 (248)

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Evaluation of the MODIS LAI/FPAR Algorithm Based on 3D-RTM Simulations: A Case Study of Grassland

Remote Sensing, 2020
Uncertainty assessment of the moderate resolution imaging spectroradiometer (MODIS) leaf area index (LAI) and the fraction of photosynthetically active radiation absorbed by vegetation (FPAR) retrieval algorithm can provide a scientific basis for the ...
Jiabin Pu, Kai Yan, Guohuan Zhou, Yongqiao Lei, Yingxin Zhu, Donghou Guo, Hanliang Li, Linlin Xu, Yuri Knyazikhin, Ranga B. Myneni   +9 more
doaj   +1 more source

Estimation of Leaf Area Index in a Typical Northern Tropical Secondary Monsoon Rainforest by Different Indirect Methods

Remote Sensing, 2023
The leaf area index (LAI) is a crucial indicator for quantifying forest productivity and community ecological processes. Satellite remote sensing can achieve large-scale LAI monitoring, but it needs to be calibrated and validated according to the in situ
Xiansheng Xie, Yuanzheng Yang, Wuzheng Li, Nanyan Liao, Weihu Pan, Hongxin Su   +5 more
doaj   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

A Phenologically Simplified Two-Stage Clumping Index Product Derived from the 8-Day Global MODIS-CI Product Suite

Remote Sensing
The clumping index (CI) is a key structural parameter that quantifies the nonrandomness of the spatial distribution of vegetation canopy leaves. Investigating seasonal variations in the CI is crucial, especially for estimating the leaf area index (LAI ...
Ge Gao, Ziti Jiao, Zhilong Li, Chenxia Wang, Jing Guo, Xiaoning Zhang, Anxin Ding, Zheyou Tan, Sizhe Chen, Fangwen Yang, Xin Dong   +10 more
doaj   +1 more source

Rotating Fluorescent Nanodiamond Assemblies With Focused Laguerre–Gaussian Beams

Advanced Optical Materials, EarlyView.
Self‐assembled fluorescent nanodiamond clusters are optically trapped and driven into controlled two‐dimensional rotation with Laguerre–Gaussian beams. With localized optical excitation, optically detected magnetic resonance spectra are collected at defined points along the orbit in a uniform external magnetic field.
Adam Stewart, Anthony J. El‐Helou, Ying Zhu, David McGloin, David A. Simpson, Peter J. Reece   +5 more
wiley   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Suitability of the boreal ecosystem simulator (BEPS) model for estimating gross primary productivity in hemi-boreal upland pine forest

Metsanduslikud Uurimused, 2022
Gross Primary Productivity (GPP) is the core component of the terrestrial and global carbon cycle and Earth’s climate research. In this study, GPP estimation was performed with the Boreal Ecosystem Productivity Simulator (BEPS) model to check its ...
Harun Fariha, Soosaar Kaido, Krasnova Alisa, Pisek Jan   +3 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source