Results 141 to 150 of about 158,776 (309)

An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation

Health Technology Assessment, 2016
Background: Care home residents with stroke-related disabilities have significant activity limitations. Phase II trial results suggested a potential benefit of occupational therapy (OT) in maintaining residents’ capacity to engage in functional activity.
Catherine M Sackley, Marion F Walker, Christopher R Burton, Caroline L Watkins, Jonathan Mant, Andrea K Roalfe, Keith Wheatley, Bart Sheehan, Leslie Sharp, Katie E Stant, Joanna Fletcher-Smith, Kerry Steel, Garry R Barton, Lisa Irvine, Guy Peryer, on behalf of the OTCH investigators   +15 more
doaj   +1 more source

GestationaL Obesity Weight management: Implementation of National Guidelines (GLOWING): a pilot cluster randomised controlled trial of a guideline implementation intervention for the management of maternal obesity by midwives

Pilot and Feasibility Studies, 2018
Background Weight management in pregnancy guidelines exist, although dissemination alone is an ineffective means of implementation. Midwives identify the need for support to overcome complex barriers to practice.
Nicola Heslehurst, Judith Rankin, Catherine McParlin, Falko F. Sniehotta, Denise Howel, Stephen Rice, Elaine McColl   +6 more
doaj   +1 more source

Explaining the effects of an intervention designed to promote evidence-based diabetes care : a theory-based process evaluation of a pragmatic cluster randomised controlled trial [PDF]

, 2008
Background The results of randomised controlled trials can be usefully illuminated by studies of the processes by which they achieve their effects. The Theory of Planned Behaviour (TPB) offers a framework for conducting such studies. This study used TPB
AE Walker, Anne Walker, Department of Health, DP French, Eileen FS Kaner, EL Deci, EL Deci, G Godin, I Ajzen, I Ajzen, I Ajzen, Jeremy M Grimshaw, Jillian J Francis, JJ Francis, KG Shojania, Liz Smith, M Eccles, Marie Johnston, Martin P Eccles, MP Eccles, MP Eccles, N Freemantle, NLD Chatzisarantis, P Sheeran, P Whitty, Paula Whitty, R Cooke, RH Fazio, The Acropolis Affirmation, UK Prospective Diabetes Study (UKPDS) Group   +29 more
core   +4 more sources

School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial

The Lancet, 2015
Suicidal behaviours in adolescents are a major public health problem and evidence-based prevention programmes are greatly needed. We aimed to investigate the efficacy of school-based preventive interventions of suicidal behaviours.The Saving and Empowering Young Lives in Europe (SEYLE) study is a multicentre, cluster-randomised controlled trial.
Wasserman, Danuta, Hoven, Christina W., WASSERMAN, Camilla Sara, Wall, Melanie, Eisenberg, Ruth, Hadlaczky, Gergö, Kelleher, Ian, SARCHIAPONE, Marco, Apter, Alan, Balazs, Judit, Bobes, Julio, Brunner, Romuald, Corcoran, Paul, Cosman, Doina, Guillemin, Francis, Haring, Christian, IOSUE, Miriam, Kaess, Michael, Kahn, Jean Pierre, Keeley, Helen, Musa, George J., Nemes, Bogdan, Postuvan, Vita, Saiz, Pilar, Reiter Theil, Stella, Varnik, Airi, Varnik, Peeter, CARLI, Vladimir   +27 more
openaire   +4 more sources

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Probiotics for preventing acute otitis media in children [PDF]

, 2018
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: to assess the effects of probiotics to prevent the occurrence and reduce the severity of acute otitis media in children.
Clark, Justin, Del Mar, Chris B., Grimwood, Keith, Islam, Farhana, Julien, Blair, Little, Paul, Roos, Kristian, Scott, Anna M.   +7 more
core   +2 more sources

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Pneumococcal conjugate vaccination schedules in infants—acquisition, immunogenicity, and pneumococcal conjugate and yellow fever vaccine co-administration study: statistical analysis plan

Trials
Rationale The effectiveness of immunisation with pneumococcal conjugate vaccine (PCV) has been demonstrated in many countries. However, the global impact of PCV is limited by its cost, which has prevented its introduction in some countries.
Grant A. Mackenzie, Isaac Osei, Rasheed Salaudeen, Paul V. Licciardi, Brian Greenwood, Kim Mulholland, Cattram Nguyen   +6 more
doaj   +1 more source

Long-term effectiveness of a multicomponent frailty management program in Singapore: One-year preliminary findings of a cluster-randomised controlled trial

Archives of Gerontology and Geriatrics Plus
The prevalence of frailty is increasing with the rapidly ageing population in Singapore. A 12-week multicomponent frailty management program, “Say No to Frailty” (SNTF) showed its feasibility and demonstrated positive outcomes.
Tianma Xu, Rhin Tok, Yan Ying Tay, Shi Ting Lai, Grace Hui Ling Tan   +4 more
doaj   +1 more source