Results 1 to 10 of about 703,659 (314)

Efficacy and safety of acupuncture for functional constipation: a randomised, sham-controlled pilot trial

BMC Complementary and Alternative Medicine, 2018
Background The prevalence of functional constipation (FC) is 3–27%, and FC has been reported to cause discomfort in daily life and various complications.
Hye-Yoon Lee, Oh-Jin Kwon, Jung-Eun Kim, Mikyeong Kim, Ae-Ran Kim, Hyo-Ju Park, Jung-Hyo Cho, Joo-Hee Kim, Sun-Mi Choi   +8 more
doaj   +1 more source

Corticosteroids for the common cold [PDF]

, 2015
BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B., Glasziou, Paul P., Hayward, Gail, Heneghan, Carl J., Perera, Rafael, Thompson, Matthew J.   +5 more
core   +1 more source

Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression

, 2013
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS).
Friede, Tim, Nicholas, Richard, Röver, Christian, Schneider, Simon, Steinvorth, Simon M., Straube, Sebastian   +5 more
core   +1 more source

Data for Thinking Healthy Programme Pakistan trial (THPP-Pakistan) [PDF]

, 2018
An anonymised dataset of 570 women (one row per woman) who gave informed consent to participate in a cluster randomised, parallel, superiority, controlled trial in Rawalpindi, Pakistan in 2014-2017. The intervention was an adapted version of the Thinking
Ahmad, Ikhlaq, Fuhr, Daniela, Patel, Vikram, Rahman, Atif, Sikander, Siham, Vanobberghen, Fiona, Weiss, Helen, Zaidi, Ahmed   +7 more
core   +1 more source

Update to: Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore

Trials
Background This trial is a parallel, two-arm, non-blinded cluster randomised controlled trial that is under way in Singapore, with the aim of measuring the efficacy of male Wolbachia-infected Aedes aegypti deployments in reducing dengue incidence in an ...
Jue Tao Lim, Diyar Mailepessov, Chee-Seng Chong, Chia-Chen Chang, Borame Dickens, Yee Ling Lai, Lu Deng, Caleb Lee, Li Yun Tan, Grace Chain, Soon Hoe Ho, Muhammad Faizal Zulkifli, Jonathan Liew, Kathryn Vasquez, Vernon Lee, Judith Chui Ching Wong, Shuzhen Sim, Cheong Huat Tan, Lee Ching Ng   +18 more
doaj   +1 more source

Understanding controlled trials: Baseline imbalance in randomised controlled trials

BMJ, 1999
In a controlled trial randomisation ensures that allocation of patients to treatments is left purely to chance. The characteristics of patients that may influence outcome are distributed between treatment groups so that any difference in outcome can be assumed to be due to the intervention.
Roberts, C., Torgerson, D. J.
openaire   +4 more sources

Facilitating return to work through early specialist health-based interventions (FRESH): protocol for a feasibility randomised controlled trial [PDF]

, 2015
Background Over one million people sustain traumatic brain injury each year in the UK and more than 10 % of these are moderate or severe injuries, resulting in cognitive and psychological problems that affect the ability to work.
A Franulic, A Relyea-Chew, A Tyerman, AH Briggs, AH Willemse-van Son, AM Salazar, AS Zigmond, B Robinson, B Willer, British Society of Rehabilitation Medicine, E Rickels, F Nouri, J Langley, J Phillips, J Possl, JK Fadyl, JM Velzen Van, JM Velzen van, JN Horton, KA Radford, LE Trexler, MC Reilly, P Deshpande, R Brooks, RD Vanderploeg, S Schonbrun, T Ownsworth   +26 more
core   +5 more sources

A falls prevention programme to improve quality of life, physical function and falls efficacy in older people receiving home help services: study protocol for a randomised controlled trial [PDF]

, 2017
BACKGROUND: Falls and fall-related injuries in older adults are associated with great burdens, both for the individuals, the health care system and the society. Previous research has shown evidence for the efficiency of exercise as falls prevention.
A Bandura, A Dadgari, A Saletti, A Vuillemin, AC Scheffer, AF Ambrose, AJ Campbell, AP Vivanti, Astrid Bergland, B Meinow, B Senn, B Vellas, C Luthy, C Meyer, C Sherrington, C-H Chou, CJ Jones, CMA Marques-Vieira, D Altman, Dawn A. Skelton, DM Landers, DM Peters, E McAuley, E McAuley, E McAuley, E McInnes, ER Vieira, ET Petridou, F El-Khoury, FB Gillison, G Salkeld, GA Kelley, HC Kraemer, I Vikman, JH Loge, K Christensen, K Delbaere, K Frändin, K Hawkins, K Haywood, KF Schulz, KF Schulz, KJ Preacher, KO Berg, L Yardley, LF Hektoen, LS Acree, LZ Rubenstein, M Bonnefoy, M Herdman, M Janssen, M Lawton, M Markle-Reid, M Ory, Maria Bjerk, MC Robertson, N Vries De, PC Fletcher, PC Fletcher, R Brooks, R Elkan, R Forkan, S Heydarnejad, S Hollis, S Michie, S Vaapio, SE Lamb, SE Lamb, SM White, SS Vaapio, T Brovold, The EuroQol Group, The WHOQOL Group, Therese Brovold, TN Tombaugh, Y Guigoz, Y Hellström, Y Netz   +77 more
core   +1 more source

Efficacy and safety of Saccharomyces boulardii in the treatment of acute gastroenteritis in the paediatric population: a systematic review

The South African Journal of Clinical Nutrition, 2019
Context: Gastroenteritis (GE) remains the second major cause of death in the most vulnerable of the world’s populations. Potential treatments include the use of probiotics, with the yeast Saccharomyces boulardii being one such option.
Morgambal Padayachee, Janicke Visser, Estelle Viljoen, Alfred Musekiwa, Renée Blaauw   +4 more
doaj   +1 more source

The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial

BMC Medical Ethics, 2018
Background The use of placebos in randomised controlled trials is a subject of considerable ethical debate. In this paper we present a set of considerations to evaluate the ethics of placebo controlled trials that includes: social value of the study ...
Phaik Yeong Cheah, Norbert Steinkamp, Lorenz von Seidlein, Ric N. Price   +3 more
doaj   +1 more source