Results 21 to 30 of about 185,473 (164)

Does prospective acceptability of an intervention influence refusal to participate in a randomised controlled trial? An interview study

Contemporary Clinical Trials Communications, 2021
Background: The generalizability of findings of Randomised Controlled Trials (RCTs) is undermined by low or biased recruitment. Reasons for participant refusal are infrequently reported in published literature. Aims: To apply the Theoretical Framework of
Mandeep Sekhon, Martin Cartwright, Sadie Lawes-Wickwar, Hayley McBain, Daniel Ezra, Stanton Newman, Jill J Francis   +6 more
doaj   +1 more source

Enhancing Recruitment Using Teleconference and Commitment Contract (ERUTECC): study protocol for a randomised, stepped-wedge cluster trial within the EFFECTS trial

Trials, 2018
Background Many randomised controlled trials (RCTs) fail to meet their recruitment goals in time. Trialists are advised to include study recruitment strategies within their trials. EFFECTS is a Swedish, academic-led RCT of fluoxetine for stroke recovery.
Erik Lundström, Eva Isaksson, Per Wester, Ann-Charlotte Laska, Per Näsman   +4 more
doaj   +1 more source

Increasing recruitment to randomised trials: a review of randomised controlled trials [PDF]

BMC Medical Research Methodology, 2006
Poor recruitment to randomised controlled trials (RCTs) is a widespread and important problem. With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective.We searched the register of
Torgerson David J, Watson Judith M
openaire   +3 more sources

Using pens as an incentive for trial recruitment of older adults: An embedded randomised controlled trial [version 1; peer review: 2 approved]

F1000Research, 2019
Background: Meeting recruitment targets for randomised controlled trials is challenging.  This trial evaluated the effectiveness of including a pen within the trial invitation pack on the recruitment of older adults into a randomised controlled trial ...
Katie Whiteside, Lydia Flett, Alex Mitchell, Caroline Fairhurst, Sarah Cockayne, Sara Rodgers, David Torgerson, OTIS Study Group   +7 more
doaj   +1 more source

Understanding randomised controlled trials [PDF]

Archives of Disease in Childhood, 2005
The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled trial, is discussed. Issues that need to be considered during the critical appraisal of randomised controlled trials, such as assessing the validity of ...
openaire   +2 more sources

Learning from OCTET – exploring the acceptability of clinical trials management methods

Trials, 2018
Background Conducting research can be time consuming, difficult and challenging. Guidance and pragmatic advice focussing on randomised controlled trial conduct are available but do not necessarily constitute comprehensive guidance.
Catherine Arundel, Judith Gellatly
doaj   +1 more source

Factors influencing participation in randomised clinical trials among patients with early Barrett’s neoplasia: a multicentre interview study

BMJ Open, 2023
Objectives Strong recruitment and retention into randomised controlled trials involving invasive therapies is a matter of priority to ensure better achievement of trial aims.
Pradeep Bhandari, Laurence B Lovat, Rehan Haidry, Krish Ragunath, Hugh Barr, Clive Stokes, Mohammad Farhad Peerally, Howard Smart, John De Caestecker, Clare Jackson   +9 more
doaj   +1 more source

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Contemporary Clinical Trials Communications, 2023
Introduction: Negative symptoms and cognitive impairment are common residual symptoms of schizophrenia that seriously affect the quality of life and social function of patients.
Anbei Lian, Qing Fan, Wenzheng Wang, Qinxin Liu, Jiacheng Shi, Min Zhuang, Yujie Li, Xiaodan Liu   +7 more
doaj   +1 more source

Randomisation methods in controlled trials

BMJ, 1998
The main purpose of randomisation is to avoid bias by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic ones such age or prognostic factors such as clinical history or disease severity.
C, Roberts, D, Torgerson
openaire   +3 more sources

IJCM_25A: Effect of one-to-one counselling of mothers attending an immunization clinic on breastfeeding among infants- A Randomised Controlled Trial

Indian Journal of Community Medicine
Background: To improve breastfeeding practices, many interventions have been studied at various critical contact points. Our study aimed to improve exclusive breastfeeding by integrating a limited number of counselling sessions with routine immunization ...
Urmimala Maiti, Khan Amir Maroof, S K Bhasin, Dheeraj Shah   +3 more
doaj   +1 more source