Results 21 to 30 of about 703,659 (314)

Manual-assisted cognitive therapy for self-harm in personality disorder and substance misuse: a feasibility trial [PDF]

, 2014
<b>Aims and method</b> To assess the feasibility of conducting a larger, definitive randomised controlled trial of manual-assisted cognitive therapy (MACT), a brief focused therapy to address self-harm and promote engagement in services.
Brown, Tom M., Davidson, Kate M., James, Vairi, Kirk, Jamie, Richardson, Julie   +4 more
core   +1 more source

Household costs of dengue illness: secondary outcomes from a randomised controlled trial of dengue prevention in Guerrero state, Mexico

BMC Public Health, 2017
Background Dengue is a serious public health problem with an important economic impact. This study used data from a cluster randomised controlled trial of community mobilisation for dengue prevention to estimate the household costs of treatment of dengue
José Legorreta-Soberanis, Sergio Paredes-Solís, Arcadio Morales-Pérez, Elizabeth Nava-Aguilera, Felipe René Serrano-de los Santos, Diana Lisseth Dimas-Garcia, Robert J Ledogar, Anne Cockcroft, Neil Andersson   +8 more
doaj   +1 more source

Design considerations for clinical trials in aphasia

Annals of Indian Academy of Neurology, 2020
The use of the randomised controlled trial (RCT) design to evaluate the effectiveness of new interventions in aphasia has increased in recent years in response to calls for high quality evidence of the effectiveness of interventions for this population ...
Rebecca Palmer
doaj   +1 more source

Does prospective acceptability of an intervention influence refusal to participate in a randomised controlled trial? An interview study

Contemporary Clinical Trials Communications, 2021
Background: The generalizability of findings of Randomised Controlled Trials (RCTs) is undermined by low or biased recruitment. Reasons for participant refusal are infrequently reported in published literature. Aims: To apply the Theoretical Framework of
Mandeep Sekhon, Martin Cartwright, Sadie Lawes-Wickwar, Hayley McBain, Daniel Ezra, Stanton Newman, Jill J Francis   +6 more
doaj   +1 more source

Increasing recruitment to randomised trials: a review of randomised controlled trials [PDF]

BMC Medical Research Methodology, 2006
Poor recruitment to randomised controlled trials (RCTs) is a widespread and important problem. With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective.We searched the register of
Torgerson David J, Watson Judith M
openaire   +3 more sources

A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol [PDF]

, 2019
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life.
Allgar, V., Cohen, J. F., Crooks, M. G., Dyson, J., English, A., Hargreaves, I., Hart, S., Hussain, J., Johnson, M., Richardson, G., Swan, F., Twiddy, M., Wright, C.   +12 more
core   +3 more sources

Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]

, 2014
Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M, Gornbein, Jeffrey, Harper, Ronald, Meymandi, Sheba, Miller, Patrick R, Schrader, Lara, Soss, Jason   +6 more
core   +1 more source

Enhancing Recruitment Using Teleconference and Commitment Contract (ERUTECC): study protocol for a randomised, stepped-wedge cluster trial within the EFFECTS trial

Trials, 2018
Background Many randomised controlled trials (RCTs) fail to meet their recruitment goals in time. Trialists are advised to include study recruitment strategies within their trials. EFFECTS is a Swedish, academic-led RCT of fluoxetine for stroke recovery.
Erik Lundström, Eva Isaksson, Per Wester, Ann-Charlotte Laska, Per Näsman   +4 more
doaj   +1 more source

Using pens as an incentive for trial recruitment of older adults: An embedded randomised controlled trial [version 1; peer review: 2 approved]

F1000Research, 2019
Background: Meeting recruitment targets for randomised controlled trials is challenging.  This trial evaluated the effectiveness of including a pen within the trial invitation pack on the recruitment of older adults into a randomised controlled trial ...
Katie Whiteside, Lydia Flett, Alex Mitchell, Caroline Fairhurst, Sarah Cockayne, Sara Rodgers, David Torgerson, OTIS Study Group   +7 more
doaj   +1 more source

Non-strategic ignorance: Considering the potential for a paradigm shift in evidence-based mental health [PDF]

, 2018
Randomised controlled trials form a central building block within the prevailing evidence-based mental health paradigm. Both methodology and paradigm have been widely problematised since their emergence in the mid-late twentieth century.
Cochrane A, Department of Health, Department of Health, Department of Health, Department of Health, Felicitas Rost, Kleinman A, Kuhn T, Latour B, Maxine Dennis, Richardson PH, Sukhjit Sidhu, Susan McPherson   +12 more
core   +1 more source