Results 11 to 20 of about 184,908 (263)
Randomised controlled trials [PDF]
Archives of Disease in Childhood, 1997 Editor,—We read with interest the recent editorial on evidence-based child health.1 We were struck by how easy it is to overlook a randomised controlled trial (RCT) in the Archives (or any other journal) if this is not indicated in the title or abstract. We wondered if this was the …
R, Phillips, T, Rothenberg
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Limitations of randomised controlled trials [PDF]
BMJ, 1995 EDITOR,—T C B Dehn has commented on the problems of accruing patients into randomised controlled trials, noting the understandable reluctance of patients to enter some trials (“I want the best treatment, doctor”) in which the patient's outcome (for example, time to death) is the main end point and, consequently, the patient is unable to benefit from ...
L P, Fielding, R, Grace, R, Hittinger
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Increasing recruitment to randomised trials: a review of randomised controlled trials [PDF]
BMC Medical Research Methodology, 2006 Poor recruitment to randomised controlled trials (RCTs) is a widespread and important problem. With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective.We searched the register of
Torgerson David J, Watson Judith M
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F1000Research, 2019 Background: Meeting recruitment targets for randomised controlled trials is challenging. This trial evaluated the effectiveness of including a pen within the trial invitation pack on the recruitment of older adults into a randomised controlled trial ...
Katie Whiteside +7 more
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Understanding randomised controlled trials [PDF]
Archives of Disease in Childhood, 2005 The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled trial, is discussed. Issues that need to be considered during the critical appraisal of randomised controlled trials, such as assessing the validity of ...
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Learning from OCTET – exploring the acceptability of clinical trials management methods
Trials, 2018 Background Conducting research can be time consuming, difficult and challenging. Guidance and pragmatic advice focussing on randomised controlled trial conduct are available but do not necessarily constitute comprehensive guidance.
Catherine Arundel, Judith Gellatly
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BMJ Open, 2023 Objectives Strong recruitment and retention into randomised controlled trials involving invasive therapies is a matter of priority to ensure better achievement of trial aims.
Pradeep Bhandari +9 more
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Contemporary Clinical Trials Communications, 2023 Introduction: Negative symptoms and cognitive impairment are common residual symptoms of schizophrenia that seriously affect the quality of life and social function of patients.
Anbei Lian +7 more
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Randomisation methods in controlled trials
BMJ, 1998 The main purpose of randomisation is to avoid bias by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic ones such age or prognostic factors such as clinical history or disease severity.
C, Roberts, D, Torgerson
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Indian Journal of Community MedicineBackground: To improve breastfeeding practices, many interventions have been studied at various critical contact points. Our study aimed to improve exclusive breastfeeding by integrating a limited number of counselling sessions with routine immunization ...
Urmimala Maiti +3 more
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