Results 11 to 20 of about 703,659 (314)
Randomised controlled trials [PDF]
Archives of Disease in Childhood, 1997 Editor,—We read with interest the recent editorial on evidence-based child health.1 We were struck by how easy it is to overlook a randomised controlled trial (RCT) in the Archives (or any other journal) if this is not indicated in the title or abstract. We wondered if this was the …
R, Phillips, T, Rothenberg
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Trials, 2022 Background Large-scale trials of multidomain interventions show that modifying lifestyle and psychological risk factors can slow cognitive decline. We aim to determine if a lower intensity, personally tailored secondary dementia prevention programme for ...
M. Poppe +20 more
doaj +1 more source
Trials, 2021 Adaptations to the gold standard randomised controlled trial (RCT) have been introduced to decrease trial costs and avoid high sample sizes. To facilitate development of precision medicine algorithms that aim to optimise treatment allocation for ...
Nils Kappelmann +2 more
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Limitations of randomised controlled trials [PDF]
BMJ, 1995 EDITOR,—T C B Dehn has commented on the problems of accruing patients into randomised controlled trials, noting the understandable reluctance of patients to enter some trials (“I want the best treatment, doctor”) in which the patient's outcome (for example, time to death) is the main end point and, consequently, the patient is unable to benefit from ...
L P, Fielding, R, Grace, R, Hittinger
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Pilot and Feasibility Studies, 2020 Background Recruitment to randomised controlled trials (RCTs) can be challenging, with most trials not reaching recruitment targets. Randomised feasibility studies can be set up prior to a main trial to identify and overcome recruitment obstacles.
Samantha Husbands +10 more
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BMC Urology, 2023 The South West Oncology Group’s 2000 randomised-control trial investigated the addition of maintenance intravesical bacillus Calmette-Guerin (BCG) to non-muscle invasive urothelial carcinoma (NMIUC) treatment. The results were published when the efficacy
Jake Tempo +2 more
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Contemporary Clinical Trials Communications, 2021 Introduction: Breastfeeding is associated with improved maternal and child outcomes. Women with a higher body mass index (BMI), who comprise about 50% of the population, are at increased risk of poorer breastfeeding practices and are a population who ...
Sharleen L. O'Reilly +23 more
doaj +1 more source
BMC Psychiatry, 2021 Background Video gaming is a promising intervention for cognitive and social impairment in patients with schizophrenia. A number of gaming interventions have been evaluated in small-scale studies with various patient groups, but studies on patients with ...
Maritta Välimäki +11 more
doaj +1 more source
The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial [PDF]
, 2013 Background: Group-based social skills training (SST) has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD). To date, no sufficiently powered randomised controlled trial has been performed to establish
Bender, Stephan +6 more
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Exploring demographic and lifestyle associations with patient experience following telephone triage by a primary care doctor or nurse:secondary analyses from a cluster randomised controlled trial [PDF]
, 2015 The ESTEEM trial was a cluster randomised controlled trial that compared two telephone triage management systems (general practitioner (GP) or a nurse supported by computer decision support software) with usual care, in response to a request for same-day
Bunn +18 more
core +2 more sources