Results 31 to 40 of about 703,659 (314)

Understanding randomised controlled trials [PDF]

Archives of Disease in Childhood, 2005
The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled trial, is discussed. Issues that need to be considered during the critical appraisal of randomised controlled trials, such as assessing the validity of ...
openaire   +2 more sources

A systematic review of randomised controlled trials on the effectiveness of exercise programs on lumbo pelvic pain among postnatal women [PDF]

, 2015
Background: A substantial number of women tend to be affected by Lumbo Pelvic Pain (LPP) following child birth. Physical exercise is indicated as a beneficial method to relieve LPP, but individual studies appear to suggest mixed findings about its ...
A Garshasbi, A Gutke, A Gutke, A Gutke, A Gutke, A Tanvi, A Vleeming, AB Granath, AG Cramp, B Stuge, B Stuge, C Richardson, CB Olsson, CB Olsson, CD Skaggs, CF Yan, CG Maher, DB Stapleton, E Kontopantelis, E Líndal, E Thorell, EC Larsen, EK Bjelland, HM McCormack, HS Robinson, HS Robinson, HY Chang, I Mogren, IM Mogren, J Walker, JM Kendall, JM Mens, JM Mens, K Björklund, K Gjestland, L Nilsson-Wikmar, L Nilsson‐Wikmar, L Norén, M Kumle, M Perry, MA Mohseni-Bandpei, Meei-Ling Gau, NA Al‐Sayegh, NC Foley, NK Vøllestad, NN Ansari, O Airaksinen, O Ayanniyi, Pei-Ching Tseng, S Chaudry, S Malmqvist, SA Olivo, Shuby Puthussery, SM Wang, WWK To, Y Ko, Yannis Pappas, YL Ko   +57 more
core   +2 more sources

Learning from OCTET – exploring the acceptability of clinical trials management methods

Trials, 2018
Background Conducting research can be time consuming, difficult and challenging. Guidance and pragmatic advice focussing on randomised controlled trial conduct are available but do not necessarily constitute comprehensive guidance.
Catherine Arundel, Judith Gellatly
doaj   +1 more source

Factors influencing participation in randomised clinical trials among patients with early Barrett’s neoplasia: a multicentre interview study

BMJ Open, 2023
Objectives Strong recruitment and retention into randomised controlled trials involving invasive therapies is a matter of priority to ensure better achievement of trial aims.
Pradeep Bhandari, Laurence B Lovat, Rehan Haidry, Krish Ragunath, Hugh Barr, Clive Stokes, Mohammad Farhad Peerally, Howard Smart, John De Caestecker, Clare Jackson   +9 more
doaj   +1 more source

A Randomised Controlled Trial [PDF]

, 2015
Liver surgery is still associated with a high rate of morbidity and mortality. We aimed to compare different haemodynamic treatments in liver surgery. In a prospective, blinded, randomised, controlled pilot trial patients undergoing liver resection were ...
Feldheiser, Aarne, Giebels, Alexander, Hunsicker, Oliver, Koch, Mandy, Pavlova, Velizara, Spies, Claudia D., Stockmann, Martin, Weimann, Karin, Wernecke, Klaus-Dieter   +8 more
core   +1 more source

Randomisation methods in controlled trials

BMJ, 1998
The main purpose of randomisation is to avoid bias by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic ones such age or prognostic factors such as clinical history or disease severity.
C, Roberts, D, Torgerson
openaire   +3 more sources

Thinking territory historically. [PDF]

, 2010
BACKGROUND: While the randomised controlled trial (RCT) is generally regarded as the design of choice for assessing the effects of health care, within the social sciences there is considerable debate about the relative suitability of RCTs and non ...
Bagnall, A, Colquitt, J, Dinnes, J, Garrett, Z, Oliver, K, Oliver, S, Rees, R, Shepherd, J, Sowden, A, Thomas, J, White, I   +10 more
core   +1 more source

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Contemporary Clinical Trials Communications, 2023
Introduction: Negative symptoms and cognitive impairment are common residual symptoms of schizophrenia that seriously affect the quality of life and social function of patients.
Anbei Lian, Qing Fan, Wenzheng Wang, Qinxin Liu, Jiacheng Shi, Min Zhuang, Yujie Li, Xiaodan Liu   +7 more
doaj   +1 more source

Effects of treatment in women with gestational diabetes mellitus : systematic review and meta-analysis [PDF]

, 2010
Objective: To summarise the benefits and harms of treatments for women with gestational diabetes mellitus. Design: Systematic review and meta-analysis of randomised controlled trials.
Horvath, Karl, Koch, Klaus, Jeitler, Klaus, Matyas, Eva, Bender, Ralf, Bastian, Hilda, Lange, Stefan, Siebenhofer-Kroitzsch, Andrea   +7 more
core   +1 more source

Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT

Health Technology Assessment, 2018
Background: Infections acquired in hospital are an important cause of morbidity and mortality in very preterm infants. Several small trials have suggested that supplementing the enteral diet of very preterm infants with lactoferrin, an antimicrobial ...
James Griffiths, Paula Jenkins, Monika Vargova, Ursula Bowler, Edmund Juszczak, Andrew King, Louise Linsell, David Murray, Christopher Partlett, Mehali Patel, Janet Berrington, Nicholas Embleton, Jon Dorling, Paul T Heath, William McGuire, Sam Oddie   +15 more
doaj   +1 more source