Results 121 to 130 of about 2,076,484 (318)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Performance evaluation of multi-core multi-cluster architecture
A multi-core cluster is a cluster composed of numbers of nodes where each node has a number of processors, each with more than one core within each single chip. Cluster nodes are connected via an interconnection network.
Walters, Robert John +4 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
In the last two decades hundreds of cluster initiatives have been launched involving virtually all regions of the world and their number is growing.
Skokan, Karel
core
To secure power system operations, practical dispatches in industries place a steady power transfer limit on critical inter-corridors, rather than high-dimensional and strong nonlinear stability constraints.
Lidong Yi +8 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Sistem Informasi Pemetaan Penghasil Cengkeh dengan Cluster pada Algoritma K-Means
Produksi cengkeh di kabupaten tolitoli yang di mana terbesar di semua kecematan, sebagai penghasil cengkeh. Peran dinas perkembunan untuk mengelompokkan dan memetakan mana yang menghasilkan produksi cengkeh, masih dalam kategori terbanyak atau pun ...
Zulkarnain, Zahir Zainuddin, Agussalim
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Since the CCM entered into force in 2010, much expertise has been acquired by States Parties and partner organisations. This expertise addresses challenges in treaty compliance and best practices that have been developed within the sector to support ...
GICHD,, Munitions, Convention on Cluster
core

