Results 81 to 90 of about 1,519,867 (319)

Cluster morphology analysis [PDF]

Spatial and Spatio-temporal Epidemiology, 2009
Most disease clustering methods assume specific shapes and do not evaluate statistical power using the applicable geography, at-risk population, and covariates. Cluster Morphology Analysis (CMA) conducts power analyses of alternative techniques assuming clusters of different relative risks and shapes.
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Euro area banking sector integration: using hierarchical cluster analysis techniques [PDF]

In this study we apply cluster analysis techniques, including a novel smoothing method, to detect some basic patterns and trends in the euro area banking sector in terms of the degree of homogeneity of countries.
Puigvert Gutiérrez, Josep Maria, Kok, Christoffer   +1 more
core  

Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study) [PDF]

, 2011
Background: the purpose of this research is to develop and evaluate methods for conducting cluster randomised trials in a primary care database that contains electronic patient records for large numbers of family practices.
Little Paul, Van Staa, Tjeerd; id_orcid, Ashworth, Maek, Delaney, Brendan, van Staa, Tjeerd, Gulliford Martin C, Moore Michael V, Judith Charlton, Paul Little, Gerard McCann, Gulliford, Martin C., Charlton, Judith, Little, Paul, Grieve, Andrew P, Ashworth Mark, Ashworth, Mark, Martin C Gulliford, Grieve Andrew P, Grieve, Andrew P., Van Staa, Tjeerd P., Dregan Alex, McCann, Gerard, Charlton Judith, electronic Cluster Randomised Trial Research Team eCRT Research, Taweel, Adel, Moore, Michael, Andrew P Grieve, Lucy Yardley, Mark Ashworth, Michael V Moore, Dregan, Alex; id_orcid, McCann Gerard, Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, McDermott, Lisa, van Staa Tjeerd, null null, Electronic Cluster Randomised Trial Research Team eCRT Research Team, Wolfe, Charles, Lisa McDermott, Yardley Lucy, Gulliford, Martin C, Rudd, Anthony, Moore, Michael V, McDermott Lisa, Alex Dregan, Moore, Michael V.   +47 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

A CLUE for CLUster ensembles

, 2005
Cluster ensembles are collections of individual solutions to a given clustering problem which are useful or necessary to consider in a wide range of applications.
Kurt Hornik, Hornik, Kurt
core   +1 more source

Network controllability analysis reveals the antiviral potential of Etravirine against hepatitis E virus infection

mSystems
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in lower- and middle-income countries. HEV infection may lead to acute liver failure, chronic liver disease, and high mortality in pregnant women.
Shabnam Ansari, Dipanka Tanu Sarmah, Rohit Verma, Kannan Chandrasekar, Shalimar, Baibaswata Nayak, Samrat Chatterjee, Milan Surjit   +7 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Cluster sample inference using sensitivity analysis: the case with few groups [PDF]

This paper re-examines inference for cluster samples. Sensitivity analysis is proposed as a new method to perform inference when the number of groups is small.
Vikström, Johan
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source