Results 1 to 10 of about 334,789 (200)

Hygiene heroes: a cluster-randomized trial of a hygiene curriculum in Tamil Nadu schools [PDF]

BMC Public Health
Background Respiratory infections and diarrheal diseases are major causes of illness and school absences for school-aged children. Both can be prevented by handwashing with soap. Unfortunately, at most schools in low-resource settings, soap and water are
David Levine, Ishira Shrivatsa, Malathy Duraisamy, Geetha Karthick   +3 more
doaj   +2 more sources

Randomization-Based Confidence Intervals for Cluster Randomized Trials [PDF]

Biostatistics, 2020
In a cluster randomized trial (CRT), groups of people are randomly assigned to different interventions. Existing parametric and semiparametric methods for CRTs rely on distributional assumptions or a large number of clusters to maintain nominal ...
Rabideau, Dustin J, Wang, Rui
core   +5 more sources

Generalized estimating equations for modeling cluster randomized trial data on smoking cessation among tuberculosis patients. [PDF]

PLoS ONE
There is a paucity of studies applying Generalized Estimating Equations (GEE) for longitudinal analysis of smoking cessation outcomes within the framework of a cluster randomized trial, especially among tuberculosis (TB) patients.
Vasantha Mahalingam, Ratnakar Singh, Ramesh Kumar Santhanakrishnan, Adhin Bhaskar, Ponnuraja Chinnaiyan   +4 more
doaj   +2 more sources

Ivermectin to reduce malaria transmission– safety and efficacy results from the BOHEMIA cluster randomized trial in MozambiqueResearch in context [PDF]

EClinicalMedicine
Summary: Background: Endectocides are a novel vector control tool that reduce the survival and fertility of blood sucking arthropods that feed upon treated humans or animals.
Carlos Chaccour, Patricia Nicolas, Samuel Martinho, Hansel Mundaca, Eldo Elobolobo, Paula Ruiz-Castillo, Amelia Houana, Julia Montaña, Jenisse Mbanze, Aina Casellas, Antonio Macucha, Mary Mael, Arlindo Soares, Caroline Kiuru, Almudena Sanz Gutierrez, Saimado Imputiua, Luis Constantino, Vegovito Vegove, Gildo Cole, Urs Duthaler, Marta Ribes, Victor Mutepa, Joe Brew, Humberto Munguambe, Sara Stanulovic, Aida Xerinda, Felisbela Materula, Nika Gorski, Caroline Wanjiku, Joanna Furnival-Adams, Laura Túnez, Leslie Sam, Lisa Collins, Kang Xia, Felix Hammann, Matthew Rudd, Cassidy Rist, Caroline Jones, Marta Maia, Baltazar Candrinho, N. Regina Rabinovich, Francisco Saute   +41 more
doaj   +2 more sources

A community-based group randomized trial to increase aspirin use for primary prevention of cardiovascular disease: Study protocol and baseline results for the “Ask About Aspirin” initiative

Contemporary Clinical Trials Communications, 2021
Background: USPSTF evidence-based recommendations for the use of low-dose aspirin for primary prevention of cardiovascular disease were published in 2009.
Sue Duval, Jeremy R. Van't Hof, Niki C. Oldenburg, Milton Eder, John R. Finnegan, Jr., Russell V. Luepker   +5 more
doaj   +1 more source

Empirical power and sample size calculations for cluster-randomized and cluster-randomized crossover studies. [PDF]

PLoS ONE, 2012
In recent years, the number of studies using a cluster-randomized design has grown dramatically. In addition, the cluster-randomized crossover design has been touted as a methodological advance that can increase efficiency of cluster-randomized studies ...
Nicholas G Reich, Jessica A Myers, Daniel Obeng, Aaron M Milstone, Trish M Perl   +4 more
doaj   +1 more source

Analysis and reporting of stratified cluster randomized trials—a systematic survey

Trials, 2020
Background In order to correctly assess the effect of intervention from stratified cluster randomized trials (CRTs), it is necessary to adjust for both clustering and stratification, as failure to do so leads to misleading conclusions about the ...
Sayem Borhan, Alexandra Papaioannou, Jinhui Ma, Jonathan Adachi, Lehana Thabane   +4 more
doaj   +1 more source

Randomized controlled trials in de-implementation research: a systematic scoping review

Implementation Science, 2022
Background Healthcare costs are rising, and a substantial proportion of medical care is of little value. De-implementation of low-value practices is important for improving overall health outcomes and reducing costs.
Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä, Kari A. O. Tikkinen   +18 more
doaj   +1 more source

Estimation of Conditional Power for Cluster-Randomized Trials with Interval-Censored Endpoints [PDF]

, 2020
Cluster-randomized trials (CRTs) of infectious disease preventions often yield correlated, interval-censored data: dependencies may exist between observations from the same cluster, and event occurrence may be assessed only at intermittent clinic visits.
Hayes R.J., Komárek A., Lan K.K.G., Proschan M.A., Turnbull B.W.   +4 more
core   +3 more sources

Age-based targeting of biannual azithromycin distribution for child survival in Niger: an adaptive cluster-randomized trial protocol (AVENIR)

BMC Public Health, 2021
Background Biannual distribution of azithromycin to children 1–59 months old reduced mortality by 14% in a cluster-randomized trial. The World Health Organization has proposed targeting this intervention to the subgroup of children 1–11 months old to ...
Kieran S. O’Brien, Ahmed M. Arzika, Abdou Amza, Ramatou Maliki, Sani Ousmane, Boubacar Kadri, Beido Nassirou, Alio Karamba Mankara, Abdoul Naser Harouna, Emily Colby, Elodie Lebas, Zijun Liu, Victoria Le, William Nguyen, Jeremy D. Keenan, Catherine E. Oldenburg, Travis C. Porco, Thuy Doan, Benjamin F. Arnold, Thomas M. Lietman, the AVENIR Study Group   +20 more
doaj   +1 more source