Results 111 to 120 of about 1,520,463 (346)
BMC Public Health, 2017 BackgroundThe prevalence of type 2 diabetes mellitus is increasing substantially worldwide, leading to serious economic effects, complications and deaths. This study evaluated the effectiveness of an empowerment program providing support for psychosocial,
D. Cortez +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
An Educational Intervention to Improve HPV Vaccination: A Cluster Randomized Trial
Pediatrics, 2018 We examine the effect of a digital educational intervention linked to previous vaccine history on HPV vaccination decisions in urban pediatric settings.
B. Dixon +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Clinical Interventions in Aging, 2023 Daphne Sze Ki Cheung,1 Paul Hong Lee,2 Claudia Kam Yuk Lai1 1School of Nursing, The Hong Kong Polytechnic University, Hong Kong; 2Southampton Clinical Trials Unit, University of Southampton, Southampton, UKCorrespondence: Daphne Sze Ki Cheung, Email ...
Cheung DSK, Lee PH, Lai CKY
doaj
Trials, 2018 Background Few papers discuss the pragmatics of conducting large, cluster randomized clinical trials. Here we describe the sequential steps taken to develop methods to implement the Randomized Evaluation of Sedation Titration for Respiratory Failure ...
Martha A. Q. Curley +8 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Effectiveness of social marketing strategies to reduce youth obesity in European school-based interventions : a systematic review and meta-analysis [PDF]
, 2016 Peer reviewedPublisher ...
Aceves Martins, Magaly +6 more
core +5 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
JAMA Internal Medicine, 2019 Importance High-quality conversations between clinicians and seriously ill patients about values and goals are associated with improved outcomes but occur infrequently.
R. Bernacki +11 more
semanticscholar +1 more source