Results 101 to 110 of about 177,862 (251)
Maize requires substantial nitrogen input, and nitrogen deficiency significantly impairs root development, reducing yield. Therefore, improving maize root system architecture under low-nitrogen (LN) conditions is critical for improving nitrogen use ...
Dongya Li, Yuanyuan Liang, Yi Wang
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
BACKGROUND: Root clusters are bunches of hairy rootlets produced by >1800 species in nine families. The possible involvement of micro-organisms in root-cluster formation has produced conflicting results over the last 40 years.
Pérez-Fernández, M., Lamont, Byron
core +1 more source
Genetic diversity analysis of rice (Oryza sativa) genotypes for seedling characters under saline - alkaline condition [PDF]
Rice is life for Asians as it provides 43 per cent calorie requirement for more than 70 per cent of the population. Theproduction is often limited by salinity.
K Seetharam, S.Thirumeni, K.Paramasivam, S.Nadaradjan
doaj
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The lactonase BxdA mediates metabolic specialisation of maize root bacteria to benzoxazinoids
Root exudates contain specialised metabolites that shape the plant’s root microbiome. How host-specific microbes cope with these bioactive compounds, and how this ability affects root microbiomes, remains largely unknown.
Lisa Thoenen +19 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Cluster roots are structures formed by many plants adapted to phosphorus (P)-deficient soils. We investigated the combined influence of spatial heterogeneity in soil water and P distribution on the allocation of cluster root formation in white lupin ...
Rainer Schulin (593796) +2 more
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source

