Results 51 to 60 of about 177,862 (251)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Digging deeper into cluster system logs for failure prediction and root cause diagnosis

open access: yes, 2014
© 2014 IEEE. As the sizes of supercomputers and data centers grow towards exascale, failures become normal. System logs play a critical role in the increasingly complex tasks of automatic failure prediction and diagnosis.
Fu, X.   +14 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Root mean square values for each cluster.

open access: yes, 2019
Root mean square values for each cluster.
Margret Bradley (6482729)   +9 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Unit root test results of four cluster variables—1st difference series.

open access: yes, 2022
Unit root test results of four cluster variables—1st difference series.
Weidong Meng (3983984)   +4 more
core   +1 more source

Genetic diversity analysis in Indian mustard (Brassica juncea L. Czern and Coss) genotypes using agro-morphological parameters

open access: yesElectronic Journal of Plant Breeding, 2017
An experiment was conducted using 45 genotypes including local cultivars, advanced lines and notified varieties of Indian mustard for genetic diversity analysis through Mahalanobis’s D2 method.
Th. Renuka Devi   +3 more
doaj   +1 more source

Root surface as criterion for selection of sugar beet [PDF]

open access: yesRatarstvo i Povrtarstvo, 2011
In this study we analyzed 10 monogerm and 10 multigerm sugar beet genotypes from the collections of the Institute of Field and Vegetable Crops in Novi Sad.
Danojević Dario   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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