Results 51 to 60 of about 177,862 (251)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Digging deeper into cluster system logs for failure prediction and root cause diagnosis
© 2014 IEEE. As the sizes of supercomputers and data centers grow towards exascale, failures become normal. System logs play a critical role in the increasingly complex tasks of automatic failure prediction and diagnosis.
Fu, X. +14 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Root mean square values for each cluster.
Root mean square values for each cluster.
Margret Bradley (6482729) +9 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Unit root test results of four cluster variables—1st difference series.
Unit root test results of four cluster variables—1st difference series.
Weidong Meng (3983984) +4 more
core +1 more source
An experiment was conducted using 45 genotypes including local cultivars, advanced lines and notified varieties of Indian mustard for genetic diversity analysis through Mahalanobis’s D2 method.
Th. Renuka Devi +3 more
doaj +1 more source
Root surface as criterion for selection of sugar beet [PDF]
In this study we analyzed 10 monogerm and 10 multigerm sugar beet genotypes from the collections of the Institute of Field and Vegetable Crops in Novi Sad.
Danojević Dario +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

