Results 81 to 90 of about 636,655 (299)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Monte Carlo Simulations of Globular Cluster Evolution. V. Binary Stellar Evolution

, 2009
We study the dynamical evolution of globular clusters containing primordial binaries, including full single and binary stellar evolution using our Monte Carlo cluster evolution code updated with an adaptation of the single and binary stellar evolution ...
Ashman, Binney, Chatterjee, Dalessandro, Davis, Demleitner, Duquennoy, Frederic A. Rasio, Fregeau, Fregeau, Fregeau, Fregeau, Hansen, Heggie, Hurley, Hwang, John M. Fregeau, Joshi, Joshi, Kroupa, Lombardi, Merritt, Noyola, Scheepmaker, Sills, Sills, Sourav Chatterjee, Spitzer, Stefan Umbreit, Trenti, Trenti   +30 more
core   +1 more source

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Locally Weighted Ensemble Clustering

, 2018
Due to its ability to combine multiple base clusterings into a probably better and more robust clustering, the ensemble clustering technique has been attracting increasing attention in recent years. Despite the significant success, one limitation to most
Huang, Dong, Lai, Jian-Huang, Wang, Chang-Dong   +2 more
core   +1 more source

Measuring the Validity of Clustering Validation Datasets

IEEE Transactions on Pattern Analysis and Machine Intelligence
Clustering techniques are often validated using benchmark datasets where class labels are used as ground-truth clusters. However, depending on the datasets, class labels may not align with the actual data clusters, and such misalignment hampers accurate validation.
Hyeon Jeon, Michaël Aupetit, DongHwa Shin, Aeri Cho, Seokhyeon Park, Jinwook Seo   +5 more
openaire   +3 more sources

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

On the Proof of Dark Matter, the Law of Gravity and the Mass of Neutrinos

, 2006
We develop a new method to predict the density associated with weak lensing maps of (un)relaxed clusters in a range of theories interpolating between GR and MOND (General Relativity and Modified Newtonian Dynamics).
Benoit Famaey, Diaz-Rivera L. M., Famaey B., Garry W. Angus, Hayashi E., Hong Sheng Zhao, Huan Yuan Shan, Pointecouteau E., Tremaine S., Zhao H. S.   +9 more
core   +2 more sources

Clustering Validation Inference

Mathematics
Clustering validation is applied to evaluate the quality of classifications. This step is crucial for unsupervised machine learning. A plethora of methods exist for this purpose; however, a common drawback is that statistical inference is not possible. In this study, we construct a density function for the cluster number.
Figuera, Pau, Cuzzocrea, Alfredo, García Bringas, Pablo   +2 more
openaire   +3 more sources

Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury

Arthritis Care &Research, EarlyView.
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years ...
Jamon L. Couch, Brooke E. Patterson, Kay M. Crossley, Ali Guermazi, Matthew G. King, Danilo De Oliveira Silva, Jackie L. Whittaker, Michael A. Girdwood, Adam G. Culvenor   +8 more
wiley   +1 more source

A numerical and analytical study of two holes doped into the 2D t--J model

, 1997
Exact diagonalization numerical results are presented for a 32-site square cluster, with two holes propagating in an antiferromagnetic background described by the t-J model. We characterize the wave function of the lowest energy bound state found in this
A.L Chernyshev, Anderson, Anderson, Belinicher, P.W Leung, R.J Gooding, Reiter   +6 more
core   +1 more source